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Literature summary extracted from

  • Jurukovski, V.; Markova, N.G.; Karaman-Jurukovska, N.; Randolph, R.K.; Su, J.; Napoli, J.L.; Simon, M.
    Cloning and characterization of retinol dehydrogenase transcripts expressed in human epidermal keratinocytes (1999), Mol. Genet. Metab., 67, 62-73.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.105 retinol dehydrogenase 4 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.105 additional information Homo sapiens the enzyme is expressed predominantly in the differentiating spinous layers and is under positive, feed-forward regulation by retinoic acid ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.105 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.105 epidermis epidermal keratinocytes, gene is expressed predominantly in the differentiating spinous layers Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.105 all-trans-retinol + NAD+
-
 Homo sapiens all-trans-retinal + NADH
-
 ?
1.1.1.105 additional information the enzyme is expressed predominantly in the differentiating spinous layers and is under positive, feed-forward regulation by retinoic acid Homo sapiens ?
-
 ?
1.1.1.105 retinol + NAD+
-
 Homo sapiens retinal + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.105 NAD+ cofactor Homo sapiens
1.1.1.105 NAD+ preferred cofactor Homo sapiens