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Literature summary extracted from

  • Langeland, B.T.; Morris, D.L.; McKinley-McKee, J.S.
    Metal binding properties of thiols: complexes with horse liver alcohol dehydrogenase (1999), Comp. Biochem. Physiol. B, 123, 155-162.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.1 1,2-dithioglycerol competitive Equus caballus
1.1.1.1 1,2-Ethanedithiol competitive Equus caballus
1.1.1.1 1,3-propanedithiol competitive Equus caballus
1.1.1.1 1,4-Butanedithiol competitive Equus caballus
1.1.1.1 1,4-dithioerythritol competitive Equus caballus
1.1.1.1 1,4-dithiothreitol competitive Equus caballus
1.1.1.1 1-hydroxypyridine-2-thione competitive Equus caballus
1.1.1.1 1-thio-1-phenylmethane competitive Equus caballus
1.1.1.1 1-thioacetamide competitive Equus caballus
1.1.1.1 1-thioacetate competitive Equus caballus
1.1.1.1 1-thiobutane competitive Equus caballus
1.1.1.1 1-thioethane competitive Equus caballus
1.1.1.1 1-thioglycerol competitive Equus caballus
1.1.1.1 1-thiopropane competitive Equus caballus
1.1.1.1 1-thiosorbitol competitive Equus caballus
1.1.1.1 2-mercapto-1-methylimidazole competitive Equus caballus
1.1.1.1 2-mercaptobenzimidazole competitive Equus caballus
1.1.1.1 2-mercaptobenzothiazole competitive Equus caballus
1.1.1.1 2-mercaptoethanol competitive Equus caballus
1.1.1.1 2-mercaptoimidazole competitive Equus caballus
1.1.1.1 2-phenylethanethiol competitive Equus caballus
1.1.1.1 2-pyridylethanethiol competitive Equus caballus
1.1.1.1 2-thioacetate competitive Equus caballus
1.1.1.1 2-thiobutane competitive Equus caballus
1.1.1.1 2-thiopropane competitive Equus caballus
1.1.1.1 2-thiopyridine competitive Equus caballus
1.1.1.1 2-thiopyrimidine competitive Equus caballus
1.1.1.1 3-mercapto-1,2,4-triazole competitive Equus caballus
1.1.1.1 3-thiopropionate competitive Equus caballus
1.1.1.1 6-thioguanine competitive Equus caballus
1.1.1.1 6-thioguanosine competitive Equus caballus
1.1.1.1 captopril competitive Equus caballus
1.1.1.1 coenzyme A competitive Equus caballus
1.1.1.1 Cys competitive Equus caballus
1.1.1.1 cysteamine competitive Equus caballus
1.1.1.1 diethyldithiocarbamate competitive Equus caballus
1.1.1.1 Disulfiram competitive Equus caballus
1.1.1.1 glutathione competitive Equus caballus
1.1.1.1 additional information thiols and dithiols have their main effect, at the enzyme-NAD+-thiol complex level, by competition with alcohol for the catalytic zinc Equus caballus
1.1.1.1 Penicillamine competitive Equus caballus
1.1.1.1 Thiophenol competitive Equus caballus
1.1.1.1 Thiourea competitive Equus caballus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.1 Equus caballus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.1 liver
-
 Equus caballus
-

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.1 NAD+
-
 Equus caballus
1.1.1.1 NADH
-
 Equus caballus