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Literature summary extracted from

  • Pocker, Y.; Li, H.
    Mechanistic enzymology of liver alcohol dehydrogenase. Kinetic and stereochemical characterization of retinal oxidation and reduction (1996), Adv. Exp.Med. Biol., 6, 331-338.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.1 0.059
-
all-trans-retinol oxidation with NAD+ Equus caballus
1.1.1.1 0.11
-
13-cis-retinal oxidation with NAD+ Equus caballus
1.1.1.1 0.137
-
13-cis-retinal reduction with NADH Equus caballus
1.1.1.1 0.16
-
9-cis-retinal oxidation with NAD+ Equus caballus
1.1.1.1 0.2
-
11-cis-retinal reduction with NADH Equus caballus
1.1.1.1 0.242
-
9-cis-retinal reduction with NADH Equus caballus
1.1.1.1 0.257
-
13-cis-retinol oxidation with NAD+ Equus caballus
1.1.1.1 0.26
-
all-trans-retinal oxidation with NAD+ Equus caballus
1.1.1.1 0.28
-
11-cis-retinol oxidation with NAD+ Equus caballus
1.1.1.1 0.3
-
9-cis-retinol oxidation with NAD+ Equus caballus
1.1.1.1 0.34
-
all-trans-retinal reduction with NADH Equus caballus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.1 Equus caballus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.1 liver
-
Equus caballus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.1 11-cis-retinol + NAD+
-
Equus caballus 11-cis-retinal + NADH
-
?
1.1.1.1 13-cis-retinol + NAD+
-
Equus caballus 13-cis-retinal + NADH
-
?
1.1.1.1 9-cis-retinol + NAD+
-
Equus caballus 9-cis-retinal + NADH
-
?
1.1.1.1 all-trans-retinal + NADH + H+
-
Equus caballus all-trans-retinol + NAD+
-
?
1.1.1.1 all-trans-retinol + NAD+
-
Equus caballus all-trans-retinal + NADH
-
?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.1 0.018
-
13-cis-retinal reduction with NADH Equus caballus
1.1.1.1 0.018
-
13-cis-retinol oxidation with NAD+ Equus caballus
1.1.1.1 0.021
-
11-cis-retinal reduction with NADH Equus caballus
1.1.1.1 0.022
-
all-trans-retinal oxidation with NAD+ Equus caballus
1.1.1.1 0.022
-
11-cis-retinol oxidation with NAD+ Equus caballus
1.1.1.1 0.023
-
9-cis-retinal reduction with NADH Equus caballus
1.1.1.1 0.025
-
9-cis-retinol oxidation with NAD+ Equus caballus
1.1.1.1 1.55
-
all-trans-retinol oxidation with NAD+ Equus caballus
1.1.1.1 2.5
-
all-trans-retinal reduction with NADH Equus caballus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.1 NAD+
-
Equus caballus
1.1.1.1 NADH
-
Equus caballus