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Literature summary extracted from

  • Yamazaki, M.; Ichikawa, Y.
    Crystallization and comparative characterization of reduced nicotinamide adenine dinucleotide phosphate-ferredoxin reductase from sheep adrenocortical mitochondria (1990), Comp. Biochem. Physiol. B, 96, 93-100.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.18.1.2 mitochondrion
-
 Ovis aries 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.18.1.2 52000
-
 minimum MW, SDS-PAGE Ovis aries
1.18.1.2 52300
-
 calculated from amino acid analysis Ovis aries

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.18.1.2 NADPH + oxidized ferredoxin Ovis aries first enzyme in mitochondrial P-450-linked monooxygenase system catalyzing several steps in the biosynthesis of steroid hormones, bile acids or vitamin D3 in various tissues NADP+ + reduced ferredoxin
-
 ?
1.18.1.2 NADPH + oxidized ferredoxin Ovis aries key enzyme catalyzing the electron transport between NADPH generated by pentose phosphate pathway and ferredoxin in plastids of plant heterotrophic tissues NADP+ + reduced ferredoxin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.18.1.2 Ovis aries
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.18.1.2 adrenal gland
-
 Ovis aries
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.18.1.2 additional information
-
-
 Ovis aries

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.18.1.2 NADPH + oxidized ferredoxin
-
 Ovis aries NADP+ + reduced ferredoxin
-
 ?
1.18.1.2 NADPH + oxidized ferredoxin first enzyme in mitochondrial P-450-linked monooxygenase system catalyzing several steps in the biosynthesis of steroid hormones, bile acids or vitamin D3 in various tissues Ovis aries NADP+ + reduced ferredoxin
-
 ?
1.18.1.2 NADPH + oxidized ferredoxin key enzyme catalyzing the electron transport between NADPH generated by pentose phosphate pathway and ferredoxin in plastids of plant heterotrophic tissues Ovis aries NADP+ + reduced ferredoxin
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.18.1.2 FAD flavoprotein Ovis aries
1.18.1.2 FAD 1 mol FAD per mol of enzyme Ovis aries