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Literature summary extracted from

  • Yuan, P.M.; Nakajin, S.; Haniu, M.; Shinoda, M.; Hall, P.F.; Shively, J.E.
    Steroid 21-hydroxylase (cytochrome P-450) from porcine adrenocorticla microsomes: microsequence analysis of cysteine-containing peptides (1983), Biochemistry, 22, 143-149.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.14.16 0.0055
-
progesterone
-
Sus scrofa
1.14.14.16 0.0055
-
17-hydroxyprogesterone
-
Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.14.16 54000
-
SDS-PAGE, chromatography on Sephadex Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.16 Sus scrofa
-
pig
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.14.16
-
Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.16 adrenal cortex
-
Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.16 17alpha-hydroxyprogesterone + NADH + O2
-
Sus scrofa 17,21-dihydroxyprogesterone + NAD+ + H2O
-
?
1.14.14.16 progesterone + NADH + O2
-
Sus scrofa deoxycorticosterone + NAD+ + H2O
-
?

Subunits

EC Number Subunits Comment Organism
1.14.14.16 More amino acid analysis, N-terminal sequence, comparison with other cytochromes P-450 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.16 heme 0.8 mol/mol peptide Sus scrofa