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Literature summary extracted from
- Adrenal microsomal hydroxylating system: purification and substrate binduing properties of cytochrome P-450C-21 (1985), Biochemistry, 24, 4287-4294.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.14.16 | microsome | - |
Bos taurus | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.14.14.16 | 52000 | - |
SDS-PAGE | Bos taurus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.16 | Bos taurus | - |
beef | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.14.14.16 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.16 | adrenal gland | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.14.14.16 | 0.003 | - |
21-hydroxylation of progesterone at 26°C | Bos taurus |
| 1.14.14.16 | 0.0038 | - |
21-hydroxylation of 17alpha-hydroxyprogesterone at 26°C | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.16 | 17alpha-hydroxyprogesterone + NADH + O2 | - |
Bos taurus | 17,21-dihydroxyprogesterone + NAD+ + H2O | - |
? |  |
| 1.14.14.16 | progesterone + NADH + O2 | - |
Bos taurus | deoxycorticosterone + NAD+ + H2O | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.14.14.16 | More | monomer-dimer equilibrium | Bos taurus |
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Release 2023.1 (January 2023)
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