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Literature summary extracted from

  • Oliw, E.H.; Su, C.; Sahlin, M.
    Catalytic properties of linoleate diol synthase of the fungus Gaeumannomyces graminis: A comparison with PGH synthases (1999), Adv. Exp. Med. Biol., 469, 679-685.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.11.60 CHAPS 0.5 mM, augments enzyme activity Gaeumannomyces graminis
1.13.11.60 Tween 20 0.04%, augments enzyme activity Gaeumannomyces graminis
5.4.4.6 CHAPS 0.5 mM, augments enzyme activity Gaeumannomyces graminis
5.4.4.6 Tween 20 0.04%, augments enzyme activity Gaeumannomyces graminis

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.60 diethyldicarbonate
-
 Gaeumannomyces graminis
1.13.11.60 Tetranitromethane 0.4 mM, 50% inhibition Gaeumannomyces graminis
5.4.4.6 diethyldicarbonate
-
 Gaeumannomyces graminis
5.4.4.6 Tetranitromethane 0.4 mM, 50% inhibition Gaeumannomyces graminis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.13.11.60 130000
-
 4 * 130000, SDS-PAGE Gaeumannomyces graminis
5.4.4.6 130000
-
 4 * 130000, SDS-PAGE Gaeumannomyces graminis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.60 linoleate + O2 Gaeumannomyces graminis
-
 (8R,10E,12Z)-8-hydroperoxy-10,12-octadecadienoate
-
 ?
5.4.4.6 (8R,9Z,12Z)-8-hydroperoxy-10,12-octadecadienoate Gaeumannomyces graminis
-
 (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.60 Gaeumannomyces graminis
-
-
-
5.4.4.6 Gaeumannomyces graminis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.60 mycelium
-
 Gaeumannomyces graminis
-
5.4.4.6 mycelium
-
 Gaeumannomyces graminis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.60 linoleate + O2
-
 Gaeumannomyces graminis (8R,10E,12Z)-8-hydroperoxy-10,12-octadecadienoate
-
 ?
5.4.4.6 (8R,9Z,12Z)-8-hydroperoxy-10,12-octadecadienoate
-
 Gaeumannomyces graminis (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate
-
 ?

Subunits

EC Number Subunits Comment Organism
1.13.11.60 tetramer 4 * 130000, SDS-PAGE Gaeumannomyces graminis
5.4.4.6 tetramer 4 * 130000, SDS-PAGE Gaeumannomyces graminis

Cofactor

EC Number Cofactor Comment Organism Structure
1.13.11.60 heme hemoptotein Gaeumannomyces graminis
5.4.4.6 heme hemoptotein Gaeumannomyces graminis