BRENDA - Enzyme Database

The hydrolysis of phosphatidylinositol monolayers at an air/water interface by the calcium-ion-dependent phosphatidylinositol phosphodiesterase of pig brain

Hirasawa, K.; Irvine, R.F.; Dawson, R.M.C.; Biochem. J. 193, 607-614 (1981)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.4.11
oleic acid
markedly increases rate of hydrolysis
Sus scrofa
3.1.4.11
oleyl alcohol
increases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as increases the rate of hydrolysis at lower pressures
Sus scrofa
3.1.4.11
phosphatidic acid
increases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as increases the rate of hydrolysis at lower pressure
Sus scrofa
3.1.4.11
phosphatidylethanolamine
slightly increases rate of hydrolysis
Sus scrofa
3.1.4.11
phosphatidylglycerol
increases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as increases the rate of hydrolysis at lower pressures
Sus scrofa
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.11
Octadecylamine
decreases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as the rate of hydrolysis below this pressures
Sus scrofa
3.1.4.11
Palmitoylcholine
decreases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as the rate of hydrolysis below this pressures
Sus scrofa
3.1.4.11
phosphatidylcholine
decreases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as the rate of hydrolysis below this pressures
Sus scrofa
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.4.11
Ca2+
required
Sus scrofa
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.4.11
Sus scrofa
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.11
brain
cerebral hemispheres
Sus scrofa
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.11
phosphatidylinositol + H2O
phosphatidylinositol monolayer at an air/water interface
285223
Sus scrofa
?
-
-
-
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.4.11
oleic acid
markedly increases rate of hydrolysis
Sus scrofa
3.1.4.11
oleyl alcohol
increases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as increases the rate of hydrolysis at lower pressures
Sus scrofa
3.1.4.11
phosphatidic acid
increases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as increases the rate of hydrolysis at lower pressure
Sus scrofa
3.1.4.11
phosphatidylethanolamine
slightly increases rate of hydrolysis
Sus scrofa
3.1.4.11
phosphatidylglycerol
increases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as increases the rate of hydrolysis at lower pressures
Sus scrofa
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.11
Octadecylamine
decreases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as the rate of hydrolysis below this pressures
Sus scrofa
3.1.4.11
Palmitoylcholine
decreases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as the rate of hydrolysis below this pressures
Sus scrofa
3.1.4.11
phosphatidylcholine
decreases the film pressure of the phosphatidylinositol monolayer at an air/water interface at which cut-off occurs, as well as the rate of hydrolysis below this pressures
Sus scrofa
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.4.11
Ca2+
required
Sus scrofa
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.11
brain
cerebral hemispheres
Sus scrofa
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.11
phosphatidylinositol + H2O
phosphatidylinositol monolayer at an air/water interface
285223
Sus scrofa
?
-
-
-
?