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Literature summary extracted from

  • Wells, T.N.C.; Coulin, F.; Payton, M.A.; Proudfoot, A.E.I.
    Phosphomannose isomerase from Saccharomyces cerevisiae contains two inhibitory metal ion binding sites (1993), Biochemistry, 32, 1294-1301.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.1.8 Cd2+ competitive, strongly pH dependent Saccharomyces cerevisiae
5.3.1.8 Hg2+ competitive, relatively pH-independent. Zn2+ and Hg2+ can simultaneously bind in the mannose 6-phosphate binding pocket, with only a small mutual repulsion Saccharomyces cerevisiae
5.3.1.8 Zn2+ competitive with mannose 6-phosphate, strongly pH-dependent. Zn2+ and Hg2+ can simultaneously bind in the mannose 6-phosphate binding pocket, with only a small mutual repulsion Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
5.3.1.8 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.1.8 D-Mannose 6-phosphate
-
Saccharomyces cerevisiae D-Fructose 6-phosphate
-
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