Any feedback?
Literature summary extracted from
- Triosephosphate isomerase from human erythrocytes (1975), Methods Enzymol., 41B, 442-447.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.1.1 | AsO43- | competitive | Homo sapiens |  |
| 5.3.1.1 | ATP | - |
Homo sapiens | |
| 5.3.1.1 | Chloroacetol phosphate | - |
Homo sapiens | |
| 5.3.1.1 | D-alpha-glycerophosphate | competitive | Homo sapiens | |
| 5.3.1.1 | Phosphoglycolate | competitive | Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.3.1.1 | 0.34 | - |
D-glyceraldehyde 3-phosphate | enzyme form I | Homo sapiens | |
| 5.3.1.1 | 0.43 | - |
D-glyceraldehyde 3-phosphate | enzyme form II | Homo sapiens | |
| 5.3.1.1 | 0.55 | - |
D-glyceraldehyde 3-phosphate | enzyme form III | Homo sapiens | |
| 5.3.1.1 | 0.69 | - |
glycerone phosphate | enzyme form III | Homo sapiens | |
| 5.3.1.1 | 0.82 | - |
glycerone phosphate | enzyme form II | Homo sapiens | |
| 5.3.1.1 | 1.5 | - |
glycerone phosphate | enzyme form I | Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.1.1 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.3.1.1 | 3 distinct electrophoretic forms: I, II, III | Homo sapiens |
Renatured (Commentary)
| EC Number | Renatured (Comment) | Organism |
|---|---|---|
| 5.3.1.1 | renaturation into catalytic active enzyme by removal of the dissociating agent | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.3.1.1 | erythrocyte | - |
Homo sapiens | - |
| 5.3.1.1 | muscle | skeletal | Homo sapiens | - |
| 5.3.1.1 | muscle | cardiac | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.3.1.1 | 10240 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.1.1 | D-Glyceraldehyde 3-phosphate | r | Homo sapiens | Glycerone phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.3.1.1 | dimer | two types of subunits possess similar but distinguishable amino acid composition, 3 electrophorectic forms: AA, AB, BB | Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.3.1.1 | 7 | 9.5 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
