Literature summary extracted from

Ahmad, S.; Fraser, J.; Sylvestre, M.; Larose, A.; Khan, A.; Bergeron, J.; Juteau, J.M.; Sondossi, M.
Sequence of the bphD gene encoding 2-hydroxy-6-oxo-(phenylchlorophenyl) hexa-2,4-dienoic acid (HOP/cPCA) hydrolase involved in the biphenyl/polychlorinated biphenyl degradation pathway in Comamonas testosteroni: evidence suggesting involvement of Ser112 in catalytic activity (1995), Gene, 156, 69-74.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.7.1.8	expression in Escherichia coli	Comamonas testosteroni

Protein Variants

EC Number	Protein Variants	Comment	Organism
3.7.1.8	S112A	inactive enzyme	Comamonas testosteroni

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.7.1.8	PMSF	inhibition of semipurified enzyme	Comamonas testosteroni

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.7.1.8	Comamonas testosteroni	Q59324	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
3.7.1.8	2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate	mechanism may involve an Asp-Ser-His catalytic triad	Comamonas testosteroni	a

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Release 2023.1 (January 2023)