Any feedback?
Literature summary extracted from
- Control of the transmembrane phospholipid distribution in eukaryotic cells by aminophospholipid translocase (1990), Biotechnol. Appl. Biochem., 12, 517-522.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.6.2.1 | NEM | - |
Homo sapiens |  |
| 7.6.2.1 | vanadate | - |
Bos taurus | |
| 7.6.2.1 | vanadate | - |
Homo sapiens | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.6.2.1 | chromaffin granule | - |
Bos taurus | 42583 | - |
| 7.6.2.1 | endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
| 7.6.2.1 | plasma membrane | plasma membrane | Homo sapiens | 5886 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.6.2.1 | Mg2+ | required | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.6.2.1 | ATP + H2O | Cavia porcellus | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | Homo sapiens | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | Rattus norvegicus | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | Sus scrofa | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | Bos taurus | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | ADP + phosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.6.2.1 | Bos taurus | - |
- |
- |
| 7.6.2.1 | Cavia porcellus | - |
- |
- |
| 7.6.2.1 | Homo sapiens | - |
- |
- |
| 7.6.2.1 | Rattus norvegicus | - |
- |
- |
| 7.6.2.1 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.6.2.1 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 7.6.2.1 | erythrocyte | - |
Homo sapiens | - |
| 7.6.2.1 | liver | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.6.2.1 | ATP + H2O | - |
Cavia porcellus | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | - |
Rattus norvegicus | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | - |
Sus scrofa | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | - |
Bos taurus | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | Cavia porcellus | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | Homo sapiens | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | Rattus norvegicus | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | Sus scrofa | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | selectively pumps the aminophospholipids phospatidylserine and phosphatidylethanolamine from the outer to the inner monolayer of eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane | Bos taurus | ADP + phosphate | - |
? | |
| 7.6.2.1 | ATP + H2O | ATPase activity is stimulated by phosphatidylserine but not by phosphatidylcholine | Homo sapiens | ADP + phosphate | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
