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Literature summary extracted from

  • Kornberg, A.; Pricer, W.E.
    Nucleotide pyrophosphatase (1950), J. Biol. Chem., 182, 763-778.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.9 5'-AMP 49% inhibition at 40 mM Solanum tuberosum
3.6.1.9 Borate strong inhibition at pH 8.5, not at pH 7.4 Solanum tuberosum
3.6.1.9 diphosphate strong inhibition at pH 8.5, not at pH 7.4 Solanum tuberosum
3.6.1.9 NADH effective inhibition of DPN splitting Solanum tuberosum
3.6.1.9 nicotinamide 19% inhibition at 100 mM Solanum tuberosum
3.6.1.9 NMN 10% inhibition at 40 mM Solanum tuberosum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.9 ATP + H2O Solanum tuberosum
-
 AMP + diphosphate
-
 ?
3.6.1.9 FAD + H2O Solanum tuberosum
-
 FMN + AMP
-
 ?
3.6.1.9 NADH + H2O Solanum tuberosum reduced and oxidized forms NMNH + AMP
-
 ?
3.6.1.9 NADP+ + H2O Solanum tuberosum
-
 nicotinamide nucleotide + adenosine 2',5'-bisphosphate
-
 ?
3.6.1.9 thiamine diphosphate + H2O Solanum tuberosum
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.9 Solanum tuberosum
-
 potato
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.9
-
 Solanum tuberosum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.9 tuber
-
 Solanum tuberosum
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.9 36.7
-
-
 Solanum tuberosum

Storage Stability

EC Number Storage Stability Organism
3.6.1.9 0-5°C, remarkably stable within 15 months Solanum tuberosum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.9 ATP + H2O
-
 Solanum tuberosum AMP + diphosphate
-
 ?
3.6.1.9 FAD + H2O
-
 Solanum tuberosum FMN + AMP
-
 ?
3.6.1.9 NADH + H2O reduced and oxidized forms Solanum tuberosum NMNH + AMP
-
 ?
3.6.1.9 NADP+ + H2O
-
 Solanum tuberosum nicotinamide nucleotide + adenosine 2',5'-bisphosphate
-
 ?
3.6.1.9 thiamine diphosphate + H2O
-
 Solanum tuberosum ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.9 6.5 8.5
-
 Solanum tuberosum

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
3.6.1.9 4
-
 50% decreased activity Solanum tuberosum
3.6.1.9 9
-
 50% decreased activity Solanum tuberosum