Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Berti, A.; Tremori, E.; Pazzagli, L.; Degl'Innocenti, D.; Camici, G.; Cappugi, G.; Manao, G.; Ramponi, G.
    Rat muscle acylphosphatase: purification, amino sequence, and immunological characterization (1991), J. Protein Chem., 10, 91-102.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.7 phosphate competitive inhibition, Ki: 3 mM Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.7 0.3
-
 benzoyl phosphate
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.7 11000
-
 SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.7 Rattus norvegicus
-
 two isoenzymes: skeletal muscle type and erythrocyte type
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.6.1.7 side-chain modification skeletal muscle, acetylated at the NH2-terminus, Ac-Ala as the NH2-terminal residue Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.7 muscle, erythrocyte type enzyme Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.1.7 muscle skeletal muscle Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.7 3281
-
 skeletal muscle, erythrocyte type enzyme Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.7 1,3-diphosphoglycerate + H2O
-
 Rattus norvegicus 3-phosphoglycerate + phosphate
-
 ?
3.6.1.7 acylphosphate + H2O specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates Rattus norvegicus carboxylate + phosphate
-
 ?
3.6.1.7 benzoyl phosphate + H2O
-
 Rattus norvegicus benzoate + phosphate
-
 ?
3.6.1.7 carbamoyl phosphate + H2O
-
 Rattus norvegicus carbamate + phosphate
-
 ?
3.6.1.7 additional information specific phosphomonohydrolase activity Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.1.7 monomer 1 * 11000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
3.6.1.7 More two isoenzymes: 1. skeletal muscle type, is present in skeletal muscle, heart, brain, liver, and in minor amounts in other tissues, 2. erythrocyte type, from red cells. The two isoenzymes clearly originated from a common ancestral gene, because about 56% of their amino acid positions in sequence are homologous Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.6.1.7 25
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.7 additional information
-
 acidic pH-optimum Rattus norvegicus
3.6.1.7 5.3
-
 assay at Rattus norvegicus
3.6.1.7 5.3
-
 pH-optimum Rattus norvegicus