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Literature summary extracted from

  • Plateau, P.; Fromant, M.; Brevet, A.; Gesquiere, A.; Blanquet, S.
    Catabolism of bis(5-nucleosidyl) oligophosphates in Escherichia coli: metal requirements and substrate specificity of homogeneous diadenosine-5,5-P1,P4-tetraphosphate pyrophosphohydrolase (1985), Biochemistry, 24, 914-922.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.41 Zn2+ exposure prior to the assay Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.6.1.41 0.012
-
 P1,P4-bis(5'-adenosyl) tetraphosphate with Mn2+ Escherichia coli
3.6.1.41 0.022
-
 P1,P4-bis(5'-adenosyl) tetraphosphate with Co2+ Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.1.41 Ca2+ no effect Escherichia coli
3.6.1.41 Co2+ 2500fold stimulation Escherichia coli
3.6.1.41 Mn2+ 900fold stimulation Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.41 33000
-
 gel filtration Escherichia coli
3.6.1.41 34000
-
 1 * 34000, SDS-PAGE Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.41 Escherichia coli
-
 EM20031
-
3.6.1.41 Escherichia coli EM20031
-
 EM20031
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.41
-
 Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.41 additional information
-
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.41 adenosine 5'-P(1)-tetraphosphate-P(4)-5'''-cytidine + H2O
-
 Escherichia coli ADP + CDP
-
 ?
3.6.1.41 adenosine 5'-P(1)-triphosphate-P(3)-5''-cytidine + H2O
-
 Escherichia coli ADP + CMP + CDP + AMP
-
 ?
3.6.1.41 adenosine 5'-P(1)-triphosphate-P(3)-5''-guanosine + H2O
-
 Escherichia coli ADP + GMP
-
 ?
3.6.1.41 Ap3A + H2O
-
 Escherichia coli ADP + AMP
-
 ?
3.6.1.41 Ap3A + H2O
-
 Escherichia coli EM20031 ADP + AMP
-
 ?
3.6.1.41 Ap4 + H2O
-
 Escherichia coli ?
-
 ?
3.6.1.41 Ap4G + H2O
-
 Escherichia coli ADP + GDP
-
 ?
3.6.1.41 diadenosine 5',5''-P1,P5-pentaphosphate + H2O
-
 Escherichia coli ADP + ATP
-
 ?
3.6.1.41 diadenosine 5',5''-P1,P5-pentaphosphate + H2O
-
 Escherichia coli EM20031 ADP + ATP
-
 ?
3.6.1.41 Gp3C + H2O
-
 Escherichia coli CDP + GMP
-
 ?
3.6.1.41 Gp3G + H2O
-
 Escherichia coli guanosine 3'-diphosphate + guanosine 5'-phosphate
-
 ?
3.6.1.41 P1,P4-bis(5'-(2'-deoxy)adenosyl)tetraphosphate + H2O
-
 Escherichia coli 2 dADP
-
 ?
3.6.1.41 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
 Escherichia coli ADP
-
 ?
3.6.1.41 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
 Escherichia coli EM20031 ADP
-
 ?
3.6.1.41 P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O
-
 Escherichia coli GTP
-
 ?
3.6.1.41 P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O
-
 Escherichia coli EM20031 GTP
-
 ?
3.6.1.41 P1,P6-di(adenosine-5')hexaphosphate + H2O
-
 Escherichia coli ADP + adenosine 5'-tetraphosphate
-
 ?
3.6.1.41 P1,P6-di(adenosine-5')hexaphosphate + H2O
-
 Escherichia coli EM20031 ADP + adenosine 5'-tetraphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.1.41 monomer 1 * 34000, SDS-PAGE Escherichia coli

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.6.1.41 250
-
 P1,P4-bis(5'-adenosyl) tetraphosphate
-
 Escherichia coli