Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Gadd, R.E.A.; Johson, W.J.
    Kinetic studies of nicotinamide deaminase from Micrococcus lysodeikticus (1974), Int. J. Biochem., 5, 397-407.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.19 5-Methylnicotinamide competitive Micrococcus luteus
3.5.1.19 EDTA 2 mM, no effect Micrococcus luteus
3.5.1.19 PCMB
-
 Micrococcus luteus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.19 0.0029
-
 nicotinamide
-
 Micrococcus luteus
3.5.1.19 0.36
-
 5'-methylnicotinamide
-
 Micrococcus luteus

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.19 Micrococcus luteus
-
 i.e. Micrococcus lysodeiktikus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.19 5-methylnicotinamide + H2O
-
 Micrococcus luteus 5-methylnicotinate + NH3
-
 ?
3.5.1.19 nicotinamide + H2O
-
 Micrococcus luteus nicotinate + NH3
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.5.1.19 37
-
 stable for more than 3 h Micrococcus luteus
3.5.1.19 50
-
 10 min, 27% loss of activity Micrococcus luteus
3.5.1.19 60
-
 10 min, 76% loss of activity Micrococcus luteus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
3.5.1.19 7 9.5 37°C, 10 min, stable Micrococcus luteus