Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Petrack, B.; Greengard, P.; Craston, N.; Sheppy, F.
    Nicotinamide deaminase from mammalian liver (1965), J. Biol. Chem., 240, 1725-1730.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.19 50
-
 nicotinamide
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.1.19 microsome
-
 Rattus norvegicus
-
-
3.5.1.19 microsome
-
 Oryctolagus cuniculus
-
-
3.5.1.19 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.19 Oryctolagus cuniculus
-
-
-
3.5.1.19 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.19
-
 Rattus norvegicus
3.5.1.19
-
 Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.19 liver
-
 Rattus norvegicus
-
3.5.1.19 liver
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.1.19 additional information
-
-
 Rattus norvegicus
3.5.1.19 additional information
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.19 nicotinamide + H2O
-
 Rattus norvegicus nicotinate + NH3
-
 ?
3.5.1.19 nicotinamide + H2O
-
 Oryctolagus cuniculus nicotinate + NH3
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.19 9 10
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.5.1.19 7 11 pH 7.0: about 35% of maximal activity, pH 11.0: about 30% of maximal activity Rattus norvegicus