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Literature summary extracted from

  • Born, T.L.; Blanchard, J.S.
    Structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis (1999), Curr. Opin. Chem. Biol., 3, 607-613.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.1.117
-
 Mycobacterium tuberculosis variant bovis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.117 succinyl-CoA + (2S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylic acid Escherichia coli involved in the biosynthesis of lysine in bacteria, blue-green algae and higher plants CoA + (2S)-2-[(3-carboxypropanoyl)amino]-6-oxoheptanedioic acid
-
 ?
2.3.1.117 succinyl-CoA + (2S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylic acid Mycobacterium tuberculosis variant bovis involved in the biosynthesis of lysine in bacteria, blue-green algae and higher plants CoA + (2S)-2-[(3-carboxypropanoyl)amino]-6-oxoheptanedioic acid
-
 ?
3.5.1.18 additional information Haemophilus influenzae structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.117 Escherichia coli
-
 enzyme is a member of the hexapeptide acyltransferase superfamily
-
2.3.1.117 Mycobacterium tuberculosis variant bovis
-
-
-
3.5.1.18 Haemophilus influenzae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.117 succinyl-CoA + (2S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylic acid involved in the biosynthesis of lysine in bacteria, blue-green algae and higher plants Escherichia coli CoA + (2S)-2-[(3-carboxypropanoyl)amino]-6-oxoheptanedioic acid
-
 ?
2.3.1.117 succinyl-CoA + (2S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylic acid involved in the biosynthesis of lysine in bacteria, blue-green algae and higher plants Mycobacterium tuberculosis variant bovis CoA + (2S)-2-[(3-carboxypropanoyl)amino]-6-oxoheptanedioic acid
-
 ?
3.5.1.18 additional information structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis Haemophilus influenzae ?
-
 ?
3.5.1.18 N-succinyl-LL-2,6-diaminoheptanedioate + H2O
-
 Haemophilus influenzae succinate + LL-2,6-diaminoheptanedioate
-
 ?