Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Munford, R.S.; Hunter, J.P.
    Acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides, has phospholipase, lysophospholipase, diacylglycerollipase, and acyltransferase activities in vitro (1992), J. Biol. Chem., 267, 10116-10121.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.77 dithiothreitol
-
 Homo sapiens
3.1.1.77 Triton X-100
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.77 2-mercaptoethanol
-
 Homo sapiens
3.1.1.77 diisopropylfluorophosphate
-
 Homo sapiens
3.1.1.77 p-bromophenacylbromide
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.77 0.00036
-
 diacylphosphatidylethanolamine
-
 Homo sapiens
3.1.1.77 0.00167
-
 lipopolysaccharide
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin Homo sapiens detoxification of LPS 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.77 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.77
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.77 HL-60 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin detoxification of LPS Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3.1.1.77 3-(acyloxy)acyl group of bacterial toxin + H2O
-
 Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
 ?
3.1.1.77 diacylglycerol + H2O in vitro Homo sapiens ?
-
 ?
3.1.1.77 diacylphosphatidylethanolamine + H2O
-
 Homo sapiens ?
-
 ?
3.1.1.77 glycerophospholipid + H2O in vitro Homo sapiens ?
-
 ?
3.1.1.77 lipopolysaccharide + H2O
-
 Homo sapiens ?
-
 ?
3.1.1.77 lysophospholipid + H2O in vitro Homo sapiens ?
-
 ?
3.1.1.77 additional information different lipids as substrates Homo sapiens ?
-
 ?
3.1.1.77 sn-1,2-dipalmitoylglycerol + H2O in vitro Homo sapiens palmitate + glycerol
-
 ?
3.1.1.77 sn-1,2-dipalmitoylphosphatidylcholine + H2O in vitro Homo sapiens palmitate + phosphatidylcholine
-
 ?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.1.77 additional information
-
 from acid to neutral pH Homo sapiens