Any feedback?
Literature summary extracted from
- Deacylation of structurally diverse lipopolysaccharides by human acyloxyacyl hydrolase (1990), J. Biol. Chem., 265, 16444-16449.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.77 | Triton X-100 | required | Homo sapiens |  |
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.1.1.77 | analysis | potential use in studies of LPS structure and bioactivity | Homo sapiens |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.1.77 | 0.00026 | - |
long chain lipopolysaccharide | - |
Homo sapiens | |
| 3.1.1.77 | 0.00031 | - |
medium chain lipopolysaccharide | - |
Homo sapiens | |
| 3.1.1.77 | 0.00032 | - |
short chain lipopolysaccharide | - |
Homo sapiens |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.77 | Ca2+ | CaCl2 enhances activity at pH 4.8 by 1.5-2 fold | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.77 | 3-(acyloxy)acyl group of bacterial toxin | Homo sapiens | detoxification of LPS | 3-hydroxyacyl group of bacterial toxin + a fatty acid | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.77 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.1.77 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.77 | HL-60 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.77 | 3-(acyloxy)acyl group of bacterial toxin | detoxification of LPS | Homo sapiens | 3-hydroxyacyl group of bacterial toxin + a fatty acid | - |
? | |
| 3.1.1.77 | 3-(acyloxy)acyl group of bacterial toxin + H2O | smooth LPS deacylated more slowly than rough LPS | Homo sapiens | 3-hydroxyacyl group of bacterial toxin + a fatty acid | palmitoleate released more slowly than myristate and laurate, 2-hydroxylaurate released more slowly than laurate | ? | |
| 3.1.1.77 | long chain lipopolysaccharide + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.1.1.77 | medium chain lipopolysaccharide + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.1.1.77 | short chain lipopolysaccharide + H2O | - |
Homo sapiens | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
