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Literature summary extracted from

  • Camp, L.A.; Hofmann, S.L.
    Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras (1993), J. Biol. Chem., 268, 22566-22574.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.2.22 diethyl dicarbonate
-
 Bos taurus
3.1.2.22 KCl
-
 Bos taurus
3.1.2.22 NaCl
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.2.22 0.01 0.02 palmitoyl-H-Ras
-
 Bos taurus
3.1.2.22 0.017
-
 palmitoyl-CoA
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.2.22 37000
-
 gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.22 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.2.22
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.22 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.22 palmitoyl-(alpha-subunit of the heterotrimeric G protein) + H2O
-
 Bos taurus palmitic acid + alpha-subunit of the heterotrimeric G protein
-
 ?
3.1.2.22 palmitoyl-CoA + H2O
-
 Bos taurus palmitate + CoA
-
 ?
3.1.2.22 palmitoyl-H-Ras + H2O the enzyme recognizes H-Ras as substrate only when H-Ras is in its native conformation Bos taurus palmitate + Ha-Ras
-
 ?
3.1.2.22 palmitoyl-[protein] + H2O
-
 Bos taurus palmitate + protein
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.2.22 monomer 1 * 37000, SDS-PAGE Bos taurus