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Literature summary extracted from

  • Jann, A.; Matsumoto, H.; Haas, D.
    The fourth arginine catabolic pathway of Pseudomonas aeruginosa [published erratum appears in J Gen Microbiol 1988 Sep;134(Pt 9):2633] (1988), J. Gen. Microbiol., 134, 1043-1053.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.54 4-guanidinobutanal + NAD+ Pseudomonas aeruginosa arginine catabolic pathway, involved in the degradation of arginine in Pseudomonas putida, cf. EC 1.2.1.19 4-guanidinobutanoate + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.19 Pseudomonas aeruginosa
-
-
-
1.2.1.54 Pseudomonas aeruginosa
-
 inducible by 2-ketoarginine
-
5.1.1.9 Pseudomonas aeruginosa
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.19 0.015
-
 L-glutamate used as growth substrate Pseudomonas aeruginosa
1.2.1.19 0.029
-
 L-arginine used as growth substrate Pseudomonas aeruginosa
1.2.1.19 0.038
-
 D-arginine used as growth substrate Pseudomonas aeruginosa
1.2.1.19 0.045
-
 4-guanidinobutyrate used as growth substrate Pseudomonas aeruginosa
1.2.1.19 0.086
-
 2-ketoarginine used as growth substrate Pseudomonas aeruginosa
1.2.1.19 0.092
-
 putrescine used as growth substrate Pseudomonas aeruginosa
1.2.1.19 0.122
-
 agmatine used as growth substrate Pseudomonas aeruginosa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.19 4-aminobutanal + NAD+ + H2O
-
 Pseudomonas aeruginosa 4-aminobutanoate + NADH + H+
-
 ?
1.2.1.19 4-guanidinobutyraldehyde + NAD+ + H2O
-
 Pseudomonas aeruginosa 4-guanidinobutyrate + NADH + H+
-
 ?
1.2.1.54 4-guanidinobutanal + NAD+
-
 Pseudomonas aeruginosa 4-guanidinobutanoate + NADH
-
 ?
1.2.1.54 4-guanidinobutanal + NAD+ arginine catabolic pathway, involved in the degradation of arginine in Pseudomonas putida, cf. EC 1.2.1.19 Pseudomonas aeruginosa 4-guanidinobutanoate + NADH
-
 ?
5.1.1.9 L-Arg
-
 Pseudomonas aeruginosa D-Arg
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.2.1.19 50
-
 for 5 min, thermal denaturation of both 4-aminobutyraldehyde dehydrogenase and 4-guanidinobutyraldehyde dehydrogenase activities observed Pseudomonas aeruginosa
1.2.1.19 60
-
 for 5 min, thermal denaturation of both 4-aminobutyraldehyde dehydrogenase and 4-guanidinobutyraldehyde dehydrogenase activities observed Pseudomonas aeruginosa

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.19 NAD+
-
 Pseudomonas aeruginosa
1.2.1.54 NAD+
-
 Pseudomonas aeruginosa