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Literature summary extracted from

  • Yoshida, H.; Hanada, K.; Ohsawa, H.; Kumagai, H.; Yamada, H.
    Biosynthetic threonine deaminase from Proteus morganii (1982), Agric. Biol. Chem., 46, 1035-1042.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.3.1.19 additional information no activation by AMP, ADP and ATP Morganella morganii

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.19 Ile Hg2+ protects Morganella morganii

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.1.19 3.2
-
 L-Thr
-
 Morganella morganii
4.3.1.19 7.1
-
 L-Ser
-
 Morganella morganii

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.3.1.19 58000
-
 4 * 58000, SDS-PAGE Morganella morganii
4.3.1.19 228000
-
 calculation from sedimentation and diffusion data Morganella morganii
4.3.1.19 230000
-
 gel filtration Morganella morganii

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.19 Morganella morganii
-
 biosynthetic threonine deaminase
-
4.3.1.19 Morganella morganii AKU 0084
-
 biosynthetic threonine deaminase
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.3.1.19
-
 Morganella morganii

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.3.1.19 318
-
-
 Morganella morganii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.19 beta-chloro-L-Ala
-
 Morganella morganii ?
-
 ?
4.3.1.19 beta-chloro-L-Ala
-
 Morganella morganii AKU 0084 ?
-
 ?
4.3.1.19 L-Cys
-
 Morganella morganii ?
-
 ?
4.3.1.19 L-Cys
-
 Morganella morganii AKU 0084 ?
-
 ?
4.3.1.19 L-serine
-
 Morganella morganii pyruvate + NH3
-
 ?
4.3.1.19 L-serine
-
 Morganella morganii AKU 0084 pyruvate + NH3
-
 ?
4.3.1.19 L-threonine
-
 Morganella morganii 2-oxobutanoate + NH3
-
 ?
4.3.1.19 L-threonine
-
 Morganella morganii AKU 0084 2-oxobutanoate + NH3
-
 ?

Subunits

EC Number Subunits Comment Organism
4.3.1.19 tetramer 4 * 58000, SDS-PAGE Morganella morganii

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.3.1.19 10
-
 with L-Thr and L-Ser as substrate Morganella morganii

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.3.1.19 8.5 11 pH 8.5: about 30% of maximal activity, pH 11.0: about 70% of maximal activity, with L-Thr as substrate Morganella morganii

Cofactor

EC Number Cofactor Comment Organism Structure
4.3.1.19 pyridoxal 5'-phosphate contains 4 mol of pyridoxal 5'-phosphate per mol of enzyme Morganella morganii
4.3.1.19 pyridoxal 5'-phosphate cofactor Morganella morganii
4.3.1.19 pyridoxal 5'-phosphate contains 2 mol of pyridoxal 5'-phosphate per mol of enzyme Morganella morganii