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Literature summary extracted from
- Universal and unique features of kinesin motors: insights from a comparison of fungal and animal conventional kinesins (1999), Biol. Chem., 380, 915-921.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 5.6.1.3 | - |
Rattus norvegicus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.6.1.3 | axon | - |
Drosophila sp. (in: flies) | 30424 | - |
| 5.6.1.3 | axon | - |
Doryteuthis pealeii | 30424 | - |
| 5.6.1.3 | endoplasmic reticulum | - |
Mus musculus | 5783 | - |
| 5.6.1.3 | endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
| 5.6.1.3 | Golgi apparatus | - |
Homo sapiens | 5794 | - |
| 5.6.1.3 | Golgi apparatus | - |
Doryteuthis pealeii | 5794 | - |
| 5.6.1.3 | lysosome | - |
Doryteuthis pealeii | 5764 | - |
| 5.6.1.3 | mitochondrion | - |
Doryteuthis pealeii | 5739 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Drosophila melanogaster | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? |  |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Drosophila sp. (in: flies) | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Mus musculus | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Homo sapiens | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Rattus norvegicus | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Bos taurus | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Neurospora crassa | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Caenorhabditis elegans | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Ustilago maydis | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Fusarium solani | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Strongylocentrotus purpuratus | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | Doryteuthis pealeii | - |
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Drosophila melanogaster | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Drosophila sp. (in: flies) | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Mus musculus | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Homo sapiens | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Rattus norvegicus | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Bos taurus | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Neurospora crassa | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Caenorhabditis elegans | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Ustilago maydis | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Fusarium solani | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Strongylocentrotus purpuratus | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | Doryteuthis pealeii | - |
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.3 | Bos taurus | - |
- |
- |
| 5.6.1.3 | Caenorhabditis elegans | - |
- |
- |
| 5.6.1.3 | Doryteuthis pealeii | - |
- |
- |
| 5.6.1.3 | Drosophila melanogaster | - |
- |
- |
| 5.6.1.3 | Drosophila sp. (in: flies) | - |
- |
- |
| 5.6.1.3 | Fusarium solani | - |
- |
- |
| 5.6.1.3 | Homo sapiens | - |
- |
- |
| 5.6.1.3 | Mus musculus | - |
- |
- |
| 5.6.1.3 | Neurospora crassa | - |
- |
- |
| 5.6.1.3 | Rattus norvegicus | - |
- |
- |
| 5.6.1.3 | Strongylocentrotus purpuratus | - |
sea urchin | - |
| 5.6.1.3 | Ustilago maydis | - |
- |
- |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Drosophila melanogaster | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Drosophila sp. (in: flies) | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Mus musculus | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Homo sapiens | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Rattus norvegicus | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Bos taurus | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Neurospora crassa | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Caenorhabditis elegans | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Ustilago maydis | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Fusarium solani | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Strongylocentrotus purpuratus | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. | Doryteuthis pealeii |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.3 | brain | - |
Mus musculus | - |
| 5.6.1.3 | brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Drosophila melanogaster | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Drosophila sp. (in: flies) | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Mus musculus | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Homo sapiens | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Rattus norvegicus | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Bos taurus | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Neurospora crassa | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Caenorhabditis elegans | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Ustilago maydis | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Fusarium solani | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Strongylocentrotus purpuratus | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | ATP + H2O + a kinesin associated with a microtubule at position n | - |
Doryteuthis pealeii | ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Drosophila melanogaster | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Drosophila sp. (in: flies) | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Mus musculus | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Homo sapiens | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Rattus norvegicus | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Bos taurus | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Neurospora crassa | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Caenorhabditis elegans | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Ustilago maydis | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Fusarium solani | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Strongylocentrotus purpuratus | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
| 5.6.1.3 | GTP + H2O + a kinesin associated with a microtubule at position n | - |
Doryteuthis pealeii | GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.6.1.3 | dimer | - |
Drosophila sp. (in: flies) |
| 5.6.1.3 | dimer | - |
Mus musculus |
| 5.6.1.3 | dimer | - |
Rattus norvegicus |
| 5.6.1.3 | dimer | SDS-PAGE | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.6.1.3 | KIF5A | - |
Mus musculus |
| 5.6.1.3 | KIF5A | - |
Homo sapiens |
| 5.6.1.3 | KIF5C | - |
Mus musculus |
| 5.6.1.3 | KIF5C | - |
Homo sapiens |
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