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Literature summary extracted from
- An essential role for katanin in severing microtubules in the neuron (1999), J. Cell Biol., 145, 305-315.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.6.1.1 | cytoplasm | - |
Rattus norvegicus | 5737 | - |
| 5.6.1.1 | cytoplasm | - |
Strongylocentrotus purpuratus | 5737 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.6.1.1 | 60000 | - |
1 * 80000 + 1 * 60000, SDS-PAGE | Rattus norvegicus |
| 5.6.1.1 | 60000 | - |
1 * 80000 + 1 * 60000, SDS-PAGE | Strongylocentrotus purpuratus |
| 5.6.1.1 | 80000 | - |
1 * 80000 + 1 * 60000, SDS-PAGE | Rattus norvegicus |
| 5.6.1.1 | 80000 | - |
1 * 80000 + 1 * 60000, SDS-PAGE | Strongylocentrotus purpuratus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.1 | ATP + H2O | Homo sapiens | - |
ADP + phosphate | - |
? |  |
| 5.6.1.1 | ATP + H2O | Rattus norvegicus | - |
ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | Strongylocentrotus purpuratus | - |
ADP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | Rattus norvegicus | - |
GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | Strongylocentrotus purpuratus | - |
GDP + phosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.1 | Homo sapiens | - |
human | - |
| 5.6.1.1 | Rattus norvegicus | - |
- |
- |
| 5.6.1.1 | Strongylocentrotus purpuratus | - |
sea urchin | - |
Reaction
| EC Number | Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|---|
| 5.6.1.1 | n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Homo sapiens | |
| 5.6.1.1 | n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Rattus norvegicus | |
| 5.6.1.1 | n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers | another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome | Strongylocentrotus purpuratus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.1 | egg | - |
Rattus norvegicus | - |
| 5.6.1.1 | egg | - |
Strongylocentrotus purpuratus | - |
| 5.6.1.1 | fibroblast | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.1 | ATP + H2O | - |
Homo sapiens | ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | - |
Rattus norvegicus | ADP + phosphate | - |
? | |
| 5.6.1.1 | ATP + H2O | - |
Strongylocentrotus purpuratus | ADP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | - |
Rattus norvegicus | GDP + phosphate | - |
? | |
| 5.6.1.1 | GTP + H2O | - |
Strongylocentrotus purpuratus | GDP + phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.6.1.1 | dimer | 1 * 80000 + 1 * 60000, SDS-PAGE | Rattus norvegicus |
| 5.6.1.1 | dimer | 1 * 80000 + 1 * 60000, SDS-PAGE | Strongylocentrotus purpuratus |
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Release 2023.1 (January 2023)
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