Any feedback?
Literature summary extracted from
- Deoxyuridine triphosphatase: a potential site of interaction with pyrimidine nucleotide analogues (1982), Biochem. Biophys. Res. Commun., 109, 746-752.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.6.1.23 | 1,10-phenanthroline | 50 mM, 30% inhibition | Homo sapiens |  |
| 3.6.1.23 | Cu2+ | - |
Homo sapiens | |
| 3.6.1.23 | EDTA | 0.5 mM, more than 90% inhibition | Homo sapiens | |
| 3.6.1.23 | EGTA | 10 mM, more than 90% inhibition | Homo sapiens | |
| 3.6.1.23 | Mn2+ | - |
Homo sapiens | |
| 3.6.1.23 | Zn2+ | - |
Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.6.1.23 | 0.003 | - |
dUTP | - |
Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.23 | 68000 | - |
gel filtration | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.23 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.6.1.23 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.6.1.23 | HeLa cell | - |
Homo sapiens | - |
| 3.6.1.23 | KB cell | - |
Homo sapiens | - |
| 3.6.1.23 | lymphoid tissue | - |
Homo sapiens | - |
| 3.6.1.23 | RAJI cell | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.23 | 0.7 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.23 | 2',3'-dideoxyUTP + H2O | 76% of the activity with dUTP | Homo sapiens | 2',3'-dideoxy-UMP + diphosphate | - |
? | |
| 3.6.1.23 | 6-azaUTP + H2O | 39% of the activity with dUTP | Homo sapiens | 6-azaUMP + diphosphate | - |
? | |
| 3.6.1.23 | araUTP + H2O | 90% of the activity with dUTP | Homo sapiens | araUMP + diphosphate | - |
? | |
| 3.6.1.23 | dUTP + H2O | - |
Homo sapiens | dUMP + diphosphate | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.6.1.23 | 6 | 9 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
