Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Robinson, A.K.; de la Pena C.E.; Barnes, L.D.
    Isolation and charcterization of diadenosine tetraphosphate (Ap4A) hydrolase from Schizosaccharomyces pombe (1993), Biochim. Biophys. Acta, 1161, 139-148.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.1.17 beta-mercaptoethanol slight activation Saccharomyces cerevisiae
3.6.1.17 dithiothreitol slight activation Saccharomyces cerevisiae
3.6.1.17 phosphate activating below 30 mM Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.17 fluoride no effect Saccharomyces cerevisiae
3.6.1.17 phosphate inhibitory above 30 mM Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.1.17 22000
-
 SDS-PAGE Saccharomyces cerevisiae
3.6.1.17 49000
-
 gel filtration Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.17 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O Saccharomyces cerevisiae
-
 ATP + AMP
-
 ?
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O Saccharomyces cerevisiae
-
 GTP + GMP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.17 Saccharomyces cerevisiae
-
 Schizosaccharomyces pombe
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.17 partial Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.17 P1,P4-bis(5'-adenosyl) tetraphosphate + H2O
-
 Saccharomyces cerevisiae ATP + AMP
-
 ?
3.6.1.17 P1,P4-bis(5'-guanosyl)tetraphosphate + H2O
-
 Saccharomyces cerevisiae GTP + GMP
-
 ?