BRENDA - Enzyme Database

A species barrier between bacteriophages T2 and T4: exclusion, join-copy and join-cut-copy recombination and mutagenesis in the dCTPase genes

Gary, T.P.; Colowick, N.E.; Mosig, G.; Genetics 148, 1461-1473 (1998)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
3.6.1.12
-
Enterobacteria phage T2
3.6.1.12
-
Escherichia virus T4
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.12
dCTP + H2O
Escherichia virus T4
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
dCMP + diphosphate
-
Escherichia virus T4
?
3.6.1.12
dCTP + H2O
Enterobacteria phage T2
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
dCMP + diphosphate
-
Enterobacteria phage T2
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.6.1.12
Enterobacteria phage T2
-
-
-
3.6.1.12
Escherichia virus T4
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.6.1.12
dCTP + H2O
-
209858
Escherichia virus T4
dCMP + diphosphate
-
209858
Escherichia virus T4
?
3.6.1.12
dCTP + H2O
-
209858
Enterobacteria phage T2
dCMP + diphosphate
-
209858
Enterobacteria phage T2
?
3.6.1.12
dCTP + H2O
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
209858
Escherichia virus T4
dCMP + diphosphate
-
209858
Escherichia virus T4
?
3.6.1.12
dCTP + H2O
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
209858
Enterobacteria phage T2
dCMP + diphosphate
-
209858
Enterobacteria phage T2
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.6.1.12
-
Enterobacteria phage T2
3.6.1.12
-
Escherichia virus T4
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.6.1.12
dCTP + H2O
Escherichia virus T4
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
dCMP + diphosphate
-
Escherichia virus T4
?
3.6.1.12
dCTP + H2O
Enterobacteria phage T2
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
dCMP + diphosphate
-
Enterobacteria phage T2
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.6.1.12
dCTP + H2O
-
209858
Escherichia virus T4
dCMP + diphosphate
-
209858
Escherichia virus T4
?
3.6.1.12
dCTP + H2O
-
209858
Enterobacteria phage T2
dCMP + diphosphate
-
209858
Enterobacteria phage T2
?
3.6.1.12
dCTP + H2O
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
209858
Escherichia virus T4
dCMP + diphosphate
-
209858
Escherichia virus T4
?
3.6.1.12
dCTP + H2O
the enzyme is essential for normal development of all T-even phages. It prevents the incorporation of dC into phage DNA by hydrolyzing dCTP and dCDP. No role of the T4 dCTPase protein in either the host-dependent or the host-independent exclusion of phage T2 by T4
209858
Enterobacteria phage T2
dCMP + diphosphate
-
209858
Enterobacteria phage T2
?