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Literature summary extracted from

  • Zimmerman, S.B.; Kornberg, A.
    Deoxycytidine di- and triphosphate cleavage by an enzyme formed in bacteriophage-infected Escherichia coli (1961), J. Biol. Chem., 236, 1480-1486.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.1.12 dCDP competitive inhibition of hydrolysis of dCTP Escherichia phage T2
3.6.1.12 dCMP competitive inhibition of hydrolysis of dCTP and dCDP Escherichia phage T2
3.6.1.12 dCTP competitive inhibition of hydrolysis of dCDP Escherichia phage T2
3.6.1.12 F-
-
 Escherichia phage T2

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.6.1.12 Mg2+ required Escherichia phage T2

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.12 Escherichia phage T2
-
 Escherichia coli infected with bacteriophage T2r+, activity found in uninfected cells is 0.1% or less of that found in uninfected cells
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.1.12
-
 Escherichia phage T2

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.6.1.12 additional information
-
-
 Escherichia phage T2

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.12 dCDP + H2O
-
 Escherichia phage T2 ?
-
 ?
3.6.1.12 dCTP + H2O
-
 Escherichia phage T2 dCMP + diphosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.6.1.12 9
-
-
 Escherichia phage T2

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.6.1.12 8 10 pH 8.0: about 55% of maximal activity, pH 10.0: about 35% of maximal activity Escherichia phage T2