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Literature summary extracted from

  • Shinohara, R.; Ishiguro, I.
    New formamidase having substrate specificity for o-formylaminoacetophenone in pig liver (1977), Biochim. Biophys. Acta, 483, 409-415.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.9 Ag+ 76% inhibition at 0.1 mM Sus scrofa
3.5.1.9 diisopropylfluorophosphate complete inhibition at 0.01 mM Sus scrofa
3.5.1.9 Hg2+ 50% inhibition at 0.1 mM Sus scrofa
3.5.1.9 L-kynurenine strong non-competitive inhibition Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.9 N-formyl-o-aminoacetophenone + H2O Cavia porcellus
-
formate + o-aminoacetophenone
-
?
3.5.1.9 N-formyl-o-aminoacetophenone + H2O Oryctolagus cuniculus
-
formate + o-aminoacetophenone
-
?
3.5.1.9 N-formyl-o-aminoacetophenone + H2O Sus scrofa the only substrate formate + o-aminoacetophenone
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.9 Cavia porcellus
-
guinea pig, formamidase II
-
3.5.1.9 no activity in Mus musculus
-
not present in liver
-
3.5.1.9 no activity in Rattus sp.
-
not present in liver
-
3.5.1.9 Oryctolagus cuniculus
-
rabbit, formamidase II
-
3.5.1.9 Sus scrofa
-
formamidase II
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.1.9 to homogeneity, chromatography techniques Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.9 liver
-
Cavia porcellus
-
3.5.1.9 liver
-
Sus scrofa
-
3.5.1.9 liver
-
Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.5.1.9 0.33
-
-
Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.9 N-formyl-o-aminoacetophenone + H2O
-
Cavia porcellus formate + o-aminoacetophenone
-
?
3.5.1.9 N-formyl-o-aminoacetophenone + H2O
-
Oryctolagus cuniculus formate + o-aminoacetophenone
-
?
3.5.1.9 N-formyl-o-aminoacetophenone + H2O the only substrate Sus scrofa formate + o-aminoacetophenone
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.9 8.5
-
-
Sus scrofa

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.5.1.9 0.1
-
Hg2+
-
Sus scrofa