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Literature summary extracted from
- Purification and assay of liver microsomal epoxide hydrase (1978), Methods Enzymol., 52, 193-200.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.3.2.9 | 1-(2-Isopropylphenyl)-imidazole | stimulates | Rattus norvegicus |  |
| 3.3.2.9 | Metyrapone | stimulates | Rattus norvegicus | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.3.2.9 | Emulgen 911 | 0.1%, 53% inhibition | Rattus norvegicus | |
| 3.3.2.9 | iodoacetamide | - |
Rattus norvegicus | |
| 3.3.2.9 | p-hydroxymercuribenzoate | - |
Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.3.2.9 | microsome | - |
Rattus norvegicus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.3.2.9 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.3.2.9 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.3.2.9 | 0.596 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.9 | 3-methylcholanthrene 11,12-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | benzoanthracene 5,6-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | benzopyrene 11,12-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Rattus norvegicus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| 3.3.2.9 | benzopyrene 7,8-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | benzopyrene 9,10-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | dibenzanthracene 5,6-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | naphthalene-1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | octene 1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | phenanthrene-9,10-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.3.2.9 | styrene 7,8-oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? | |
| 3.3.2.9 | styrene oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? | |
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