EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.3.2.9 | 1(2-naphthyl)-2-phenylethanedione | stimulates | Rattus norvegicus | |
3.3.2.9 | benzil | stimulates | Rattus norvegicus | |
3.3.2.9 | chalcone epoxide | stimulates | Rattus norvegicus | |
3.3.2.9 | clotrimazole | stimulates | Rattus norvegicus | |
3.3.2.9 | ellipticine | stimulates | Rattus norvegicus | |
3.3.2.9 | flavone | stimulates | Rattus norvegicus | |
3.3.2.9 | Harmane | stimulates | Rattus norvegicus | |
3.3.2.9 | Isoquinoline | stimulates | Rattus norvegicus | |
3.3.2.9 | Metyrapone | - |
Oryctolagus cuniculus | |
3.3.2.9 | Metyrapone | stimulates | Rattus norvegicus | |
3.3.2.9 | nitroanisil | stimulates | Rattus norvegicus | |
3.3.2.9 | norharmane | stimulates | Rattus norvegicus | |
3.3.2.9 | p-anisil | stimulates | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.3.2.9 | microsome | - |
Rattus norvegicus | - |
- |
3.3.2.9 | microsome | - |
Oryctolagus cuniculus | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.3.2.9 | additional information | Rattus norvegicus | enzyme is involved in the metabolism of steroids, the microsomal enzyme plays a central role in both the inactivation of primary mutagenic and carcinogenic metabolites of polycyclic aromatic hydrocarbons, and in activating these metabolites to even more toxic or mutagenic secondary products, enzyme production is induced by 3-methylcholanthrene, phenobarbital, trans-stilbene oxide, 2(3)-tert-butyl-4-hydroxyanisol or 2-acetylaminofluorene | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.3.2.9 | Oryctolagus cuniculus | - |
- |
- |
3.3.2.9 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.3.2.9 | liver | - |
Rattus norvegicus | - |
3.3.2.9 | liver | - |
Oryctolagus cuniculus | - |
EC Number | Storage Stability | Organism |
---|---|---|
3.3.2.9 | 0°C, 50 mM sodium phosphate buffer, pH 7.0, 2 months, stable | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | 1,2,3,4,9,9-hexachloro-6,7-epoxy-1,4,41,5,6,7,8,8a-octahydro-1,4-methanonaphthalene + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
3.3.2.9 | androstene oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | benzene oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | benzoanthracene 5,6-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | benzopyrene 11,12-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Rattus norvegicus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
3.3.2.9 | benzopyrene 4,5-oxide + H2O | - |
Oryctolagus cuniculus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
3.3.2.9 | benzopyrene 7,8-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | benzopyrene 9,10-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | cis-stilbene oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | cis-stilbene oxide + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
3.3.2.9 | dibenzoanthracene + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | estroxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | additional information | enzyme is involved in the metabolism of steroids, the microsomal enzyme plays a central role in both the inactivation of primary mutagenic and carcinogenic metabolites of polycyclic aromatic hydrocarbons, and in activating these metabolites to even more toxic or mutagenic secondary products, enzyme production is induced by 3-methylcholanthrene, phenobarbital, trans-stilbene oxide, 2(3)-tert-butyl-4-hydroxyanisol or 2-acetylaminofluorene | Rattus norvegicus | ? | - |
? | |
3.3.2.9 | naphthalene-1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | octene 1,2-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | phenanthrene-9,10-oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | styrene 7,8-oxide + H2O | - |
Rattus norvegicus | styrene glycol | - |
? | |
3.3.2.9 | trans-ethyl styrene oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.3.2.9 | trans-ethyl styrene oxide + H2O | - |
Oryctolagus cuniculus | ? | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.3.2.9 | 8.9 | 9.4 | hydration of styrene 7,8-oxide | Rattus norvegicus |