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Literature summary extracted from

  • Sternberg, M.; Spiro, R.G.
    Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney alpha-glucosidase of high specificity (1979), J. Biol. Chem., 254, 10329-10336.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.107 D-glucono-1,5-lactone 10 mM complete inhibition Rattus norvegicus
3.2.1.107 NaCl 0.8 mM 62% inhibition Rattus norvegicus
3.2.1.107 p-chloromercuribenzoate 1 mM complete inhibition Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.107 5.7
-
 2-O-Alpha-D-glucopyranosyl-O-beta-D-galactopyranosylhydroxylysine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.107 Rattus norvegicus
-
 male albino rat Charles River CD strain
-
3.2.1.107 Rattus norvegicus Charles River CD
-
 male albino rat Charles River CD strain
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.107
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.107 kidney
-
 Rattus norvegicus
-
3.2.1.107 renal cortex
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.107 additional information
-
 highest activity in the kidneys of neonatal rats and decreases with age Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.107 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosylhydroxylysine + H2O
-
 Rattus norvegicus alpha-D-glucose + beta-D-galactopyranosyl-L-hydroxylysine
-
 ?
3.2.1.107 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosylhydroxylysine + H2O
-
 Rattus norvegicus Charles River CD alpha-D-glucose + beta-D-galactopyranosyl-L-hydroxylysine
-
 ?
3.2.1.107 isomaltose + H2O
-
 Rattus norvegicus ?
-
 ?
3.2.1.107 isomaltose + H2O
-
 Rattus norvegicus Charles River CD ?
-
 ?
3.2.1.107 kojibiose + H2O
-
 Rattus norvegicus alpha-D-glucose + D-glucose
-
 ?
3.2.1.107 kojibiose + H2O
-
 Rattus norvegicus Charles River CD alpha-D-glucose + D-glucose
-
 ?
3.2.1.107 maltose + H2O
-
 Rattus norvegicus alpha-D-glucose + D-glucose
-
 ?
3.2.1.107 maltose + H2O
-
 Rattus norvegicus Charles River CD alpha-D-glucose + D-glucose
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.107 4.4 4.7
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.2.1.107 3.9 5.8 pH 3.9 and 5.8, 50% of maximal activity Rattus norvegicus