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Literature summary extracted from

  • Robinson, A.K.; Barnes, L.D.
    Three diadenosine 5',5'''-P1,P4-tetraphosphate hydrolytic enzymes from Physarum polycephalum with differential effects by calcium: a specific dinucleoside polyphosphate pyrophosphohydrolase, a nucleotide pyrophosphatase, and a phosphodiesterase (1986), Arch. Biochem. Biophys., 248, 502-515.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.1 EGTA
-
 Physarum polycephalum
3.1.4.1 Zn2+
-
 Physarum polycephalum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.1 Ca2+ activation, 50-60 times more stimulatory than Mg2+ or Mn2+ Physarum polycephalum
3.1.4.1 Co2+ no significant effect Physarum polycephalum
3.1.4.1 divalent cations activation Physarum polycephalum
3.1.4.1 Mg2+ slight activation Physarum polycephalum
3.1.4.1 Mn2+ slight activation Physarum polycephalum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.4.1 45300
-
 gel filtration Physarum polycephalum

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.1 Physarum polycephalum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.1 partial Physarum polycephalum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.1 plasmodium microplasmodium Physarum polycephalum
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.4.1 0.169
-
-
 Physarum polycephalum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.1 adenosine 5'-P1-tetraphospho-P4-5'''-adenosine + H2O
-
 Physarum polycephalum AMP + ATP
-
 ?
3.1.4.1 adenosine 5'-P1-tetraphospho-P4-5'''-guanosine + H2O
-
 Physarum polycephalum ?
-
 ?
3.1.4.1 ADP + H2O
-
 Physarum polycephalum AMP + phosphate
-
 ?
3.1.4.1 ATP + H2O
-
 Physarum polycephalum 5'-AMP + diphosphate
-
 ?
3.1.4.1 bis(p-nitrophenyl) phosphate + H2O
-
 Physarum polycephalum ?
-
 ?
3.1.4.1 dinucleoside polyphosphate + H2O
-
 Physarum polycephalum ?
-
 ?
3.1.4.1 additional information broad substrate specificity Physarum polycephalum ?
-
 ?
3.1.4.1 NADP+ + H2O
-
 Physarum polycephalum NAD+ + phosphate
-
 ?
3.1.4.1 p-nitrophenyl phenylphosphonate + H2O
-
 Physarum polycephalum p-nitrophenol + benzenephosphonic acid
-
 ?
3.1.4.1 p-nitrophenylthymidine 5'-phosphate + H2O
-
 Physarum polycephalum 5'-TMP + p-nitrophenol
-
 ?