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Literature summary extracted from

  • Yamaguchi, T.; Choi, S.Y.; Okada, H.; Yohda, M.; Kumagai, H.; Esaki, N.; Soda, K.
    Properties of aspartate racemase, a pyridoxal 5'-phosphate-independent amino acid racemase (1992), J. Biol. Chem., 267, 18361-18364.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.1.1.13 additional information enzyme contains no bound pyridoxal phosphate Streptococcus thermophilus

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.1.1.13 2-Nitro-5-thiocyanobenzoate
-
 Streptococcus thermophilus
5.1.1.13 5,5'-dithiobis(2-nitrobenzoate)
-
 Streptococcus thermophilus
5.1.1.13 iodoacetamide
-
 Streptococcus thermophilus
5.1.1.13 iodoacetate
-
 Streptococcus thermophilus
5.1.1.13 additional information enzyme is not influenced by high concentrations of aspartate up to 500 mM Streptococcus thermophilus
5.1.1.13 NEM
-
 Streptococcus thermophilus
5.1.1.13 p-chloromercuribenzoate
-
 Streptococcus thermophilus
5.1.1.13 thiol reagents
-
 Streptococcus thermophilus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.1.1.13 8.7
-
 D-Asp
-
 Streptococcus thermophilus
5.1.1.13 35
-
 L-Asp
-
 Streptococcus thermophilus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.1.1.13 additional information enzyme contains no significant amount of metal Streptococcus thermophilus

Organism

EC Number Organism UniProt Comment Textmining
5.1.1.13 Streptococcus thermophilus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.1.1.13
-
 Streptococcus thermophilus

Reaction

EC Number Reaction Comment Organism Reaction ID
5.1.1.13 L-aspartate = D-aspartate removal of alpha-hydrogen of the substrate is at least partially rate-determining Streptococcus thermophilus
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.1.1.13 L-Ala no racemase activity Streptococcus thermophilus D-Ala
-
 ?
5.1.1.13 L-Asp
-
 Streptococcus thermophilus D-Asp
-
 ?
5.1.1.13 L-Cysteate at 88% of the activity relative to L-Asp Streptococcus thermophilus D-Cysteate
-
 ?
5.1.1.13 L-Cysteine sulfinate at 51% of the activity relative to L-Asp Streptococcus thermophilus D-Cysteine sulfinate
-
 ?
5.1.1.13 additional information no racemase activity with Asp, Cys, Pro, and hydroxyproline Streptococcus thermophilus ?
-
 ?