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Literature summary extracted from

  • Lau, E.P.; Cochran, B.C.; Munson, L.; Fall, R.R.
    Bovine kidney 3-methylcrotonyl-CoA and propionyl-CoA carboxylase: each enzyme contains nonidentical subunits (1979), Proc. Natl. Acad. Sci. USA, 76, 214-218.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.4.1.3 mitochondrion
-
 Bos taurus 5739
-
6.4.1.4 mitochondrion
-
 Bos taurus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.4.1.3 58000
-
 x * 74000, biotin-containing, + x * 58000, SDS-PAGE Bos taurus
6.4.1.3 74000
-
 x * 74000, biotin-containing, + x * 58000, SDS-PAGE Bos taurus
6.4.1.4 62000
-
 x * 62000, biotin-free subunit, + x * 80000, biotin-containing subunit, SDS-PAGE Bos taurus
6.4.1.4 80000
-
 x * 62000, biotin-free subunit, + x * 80000, biotin-containing subunit, SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.3 Bos taurus
-
-
-
6.4.1.3 Sus scrofa
-
-
-
6.4.1.4 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.4.1.4
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.4.1.3 heart
-
 Bos taurus
-
6.4.1.3 kidney
-
 Bos taurus
-
6.4.1.4 kidney
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.3 ATP + propanoyl-CoA + HCO3-
-
 Sus scrofa ADP + phosphate + methylmalonyl-CoA
-
 ?
6.4.1.3 ATP + propanoyl-CoA + HCO3-
-
 Bos taurus ADP + phosphate + methylmalonyl-CoA
-
 ?
6.4.1.4 ATP + 3-methylcrotonoyl-CoA + HCO3-
-
 Bos taurus ADP + phosphate + 3-methylglutaconyl-CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
6.4.1.3 ? x * 74000, biotin-containing, + x * 58000, SDS-PAGE Bos taurus
6.4.1.4 ? x * 62000, biotin-free subunit, + x * 80000, biotin-containing subunit, SDS-PAGE Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
6.4.1.3 biotin biotin-containing enzyme Sus scrofa
6.4.1.3 biotin biotin-containing enzyme Bos taurus
6.4.1.4 biotin enzyme contains biotin Bos taurus
6.4.1.4 biotin biotin is bound to the heavier subunit Bos taurus