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Literature summary extracted from
- Partial purification and some properties of pyruvate carboxylase from the flight muscle of the locust Schistocerca gregaria (1978), Biochim. Biophys. Acta, 522, 270-275.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 6.4.1.1 | acetyl-CoA | activates | Rattus norvegicus |  |
| 6.4.1.1 | acetyl-CoA | activates | Schistocerca gregaria | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 6.4.1.1 | additional information | insensitive to inhibition by di- and tricarboxylic acids | Schistocerca gregaria |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 6.4.1.1 | 0.14 | - |
ATP | - |
Schistocerca gregaria | |
| 6.4.1.1 | 0.19 | - |
ATP | - |
Rattus norvegicus | |
| 6.4.1.1 | 0.24 | - |
ATP | pyruvate | Rattus norvegicus | |
| 6.4.1.1 | 0.25 | - |
pyruvate | pyruvate | Schistocerca gregaria | |
| 6.4.1.1 | 0.27 | - |
HCO3- | pyruvate | Tenebrio molitor | |
| 6.4.1.1 | 0.32 | - |
ATP | - |
Schistocerca gregaria | |
| 6.4.1.1 | 1.5 | - |
HCO3- | - |
Tenebrio molitor | |
| 6.4.1.1 | 2.7 | - |
HCO3- | - |
Rattus norvegicus | |
| 6.4.1.1 | 16.1 | - |
HCO3- | - |
Schistocerca gregaria | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 6.4.1.1 | Rattus norvegicus | - |
- |
- |
| 6.4.1.1 | Schistocerca gregaria | - |
- |
- |
| 6.4.1.1 | Tenebrio molitor | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 6.4.1.1 | partial | Schistocerca gregaria |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 6.4.1.1 | flight muscle | - |
Schistocerca gregaria | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 6.4.1.1 | ATP + pyruvate + HCO3- | - |
Rattus norvegicus | ADP + phosphate + oxaloacetate | - |
? | |
| 6.4.1.1 | ATP + pyruvate + HCO3- | - |
Schistocerca gregaria | ADP + phosphate + oxaloacetate | - |
? | |
| 6.4.1.1 | ATP + pyruvate + HCO3- | - |
Tenebrio molitor | ADP + phosphate + oxaloacetate | - |
? | |
| 6.4.1.1 | ATP + pyruvate + HCO3- | ATP in form of MgATP2- | Rattus norvegicus | ADP + phosphate + oxaloacetate | - |
? | |
| 6.4.1.1 | ATP + pyruvate + HCO3- | ATP in form of MgATP2- | Schistocerca gregaria | ADP + phosphate + oxaloacetate | - |
? | |
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Release 2023.1 (January 2023)
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