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Literature summary extracted from

  • Zielke, C.L.; Suelter, C.H.
    Purine, purine nucleoside, and purine nucleotide aminohydrolases (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 4, 47-78.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.4.18 beta,beta-dimethyl glutarate 3,2 mM Desulfovibrio desulfuricans
3.5.4.18 cacodylate 134 mM Desulfovibrio desulfuricans
3.5.4.18 citrate 6 mM Desulfovibrio desulfuricans
3.5.4.18 diphosphate
-
 Microsporum audouinii
3.5.4.18 Fe3+
-
 Microsporum audouinii
3.5.4.18 Maleate 22 mM Desulfovibrio desulfuricans
3.5.4.18 phosphate 83 mM Desulfovibrio desulfuricans
3.5.4.18 phosphate
-
 Microsporum audouinii
3.5.4.18 succinate 18 mM Desulfovibrio desulfuricans
3.5.4.18 Triphosphate
-
 Microsporum audouinii

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.4.18 0.25
-
 AMP
-
 Desulfovibrio desulfuricans
3.5.4.18 0.29
-
 ATP
-
 Desulfovibrio desulfuricans
3.5.4.18 0.3
-
 ADP
-
 Desulfovibrio desulfuricans
3.5.4.18 0.69
-
 adenosine
-
 Desulfovibrio desulfuricans
3.5.4.18 59
-
 NAD+
-
 Desulfovibrio desulfuricans

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.4.18 Ca2+ divalent cations, Mg2+, Ba2+ Porphyra crispata

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.2 adenine + H2O Cyberlindnera jadinii
-
 ?
-
 ?
3.5.4.18 ATP + H2O Desulfovibrio desulfuricans
-
 ITP + NH3
-
 ?
3.5.4.18 ATP + H2O Porphyra crispata
-
 ITP + NH3
-
 ?
3.5.4.18 ATP + H2O Microsporum audouinii
-
 ITP + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.2 Cyberlindnera jadinii
-
-
-
3.5.4.18 Desulfovibrio desulfuricans
-
-
-
3.5.4.18 Microsporum audouinii
-
-
-
3.5.4.18 Porphyra crispata
-
 red marine alga
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.2 adenine + H2O
-
 Cyberlindnera jadinii hypoxanthine + NH3
-
 ?
3.5.4.2 adenine + H2O
-
 Cyberlindnera jadinii ?
-
 ?
3.5.4.18 3',5'-cyclic AMP + H2O
-
 Microsporum audouinii ?
-
 ?
3.5.4.18 3'-AMP + H2O
-
 Microsporum audouinii 3'-IMP + NH3
-
 ?
3.5.4.18 5'-adenosine acetate + H2O
-
 Microsporum audouinii 5'-inosine acetate + NH3
-
 ?
3.5.4.18 5'-adenosine propionate + H2O
-
 Microsporum audouinii 5'-inosine propionate
-
 ?
3.5.4.18 adenosine + H2O
-
 Desulfovibrio desulfuricans inosine + NH3
-
 ?
3.5.4.18 adenosine + H2O
-
 Porphyra crispata inosine + NH3
-
 ?
3.5.4.18 adenosine + H2O
-
 Microsporum audouinii inosine + NH3
-
 ?
3.5.4.18 adenosine 5'-monosulfate + H2O
-
 Microsporum audouinii inosine 5'-monosulfate + NH3
-
 ?
3.5.4.18 ADP + H2O
-
 Desulfovibrio desulfuricans IDP + NH3
-
 ?
3.5.4.18 ADP + H2O
-
 Porphyra crispata IDP + NH3
-
 ?
3.5.4.18 ADP + H2O
-
 Microsporum audouinii IDP + NH3
-
 ?
3.5.4.18 ADP-glucose + H2O
-
 Microsporum audouinii IDP-glucose + NH3
-
 ?
3.5.4.18 ADPribose + H2O
-
 Desulfovibrio desulfuricans IDPribose + NH3
-
 ?
3.5.4.18 ADPribose + H2O
-
 Microsporum audouinii IDPribose + NH3
-
 ?
3.5.4.18 AMP + H2O
-
 Desulfovibrio desulfuricans IMP + NH3
-
 ?
3.5.4.18 AMP + H2O
-
 Porphyra crispata IMP + NH3
-
 ?
3.5.4.18 AMP + H2O
-
 Microsporum audouinii IMP + NH3
-
 ?
3.5.4.18 ATP + H2O
-
 Desulfovibrio desulfuricans ITP + NH3
-
 ?
3.5.4.18 ATP + H2O
-
 Porphyra crispata ITP + NH3
-
 ?
3.5.4.18 ATP + H2O
-
 Microsporum audouinii ITP + NH3
-
 ?
3.5.4.18 CoA + H2O
-
 Microsporum audouinii ?
-
 ?
3.5.4.18 dADP + H2O
-
 Desulfovibrio desulfuricans dIDP + NH3
-
 ?
3.5.4.18 dADP + H2O
-
 Microsporum audouinii dIDP + NH3
-
 ?
3.5.4.18 dAMP + H2O
-
 Desulfovibrio desulfuricans dIMP + NH3
-
 ?
3.5.4.18 dAMP + H2O
-
 Microsporum audouinii dIMP + NH3
-
 ?
3.5.4.18 dATP + H2O
-
 Desulfovibrio desulfuricans dITP + NH3
-
 ?
3.5.4.18 dATP + H2O
-
 Microsporum audouinii dITP + NH3
-
 ?
3.5.4.18 deoxyadenosine + H2O
-
 Desulfovibrio desulfuricans deoxyinosine + NH3
-
 ?
3.5.4.18 FAD + H2O
-
 Microsporum audouinii ?
-
 ?
3.5.4.18 NAD+ + H2O
-
 Desulfovibrio desulfuricans inosine nicotinamide dinucleotide + NH3
-
 ?
3.5.4.18 NAD+ + H2O
-
 Porphyra crispata inosine nicotinamide dinucleotide + NH3
-
 ?
3.5.4.18 NAD+ + H2O
-
 Microsporum audouinii inosine nicotinamide dinucleotide + NH3
-
 ?