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Literature summary extracted from
- Ganglioside GM3 sialidase activity in fibroblasts of normal individuals and of patients with sialidosis and mucolipidosis IV (1989), Biochem. J., 260, 69-74.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.1.18 | cholate | - |
Homo sapiens |  |
| 3.2.1.18 | Triton X-100 | - |
Homo sapiens | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.1.18 | Cu2+ | - |
Homo sapiens | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.2.1.18 | lysosome | - |
Homo sapiens | 5764 | - |
| 3.2.1.18 | plasma membrane | - |
Homo sapiens | 5886 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.18 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.1.18 | fibroblast | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.18 | 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O | - |
Homo sapiens | 4-methylumbelliferone + N-acetylneuraminic acid | - |
? | |
| 3.2.1.18 | ganglioside GM3 + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.2.1.18 | sialyloligosaccharides + H2O | - |
Homo sapiens | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.18 | 4.5 | - |
- |
Homo sapiens |
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