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Literature summary extracted from

  • Zamarripa-Morales, S.; Villagomez-Castro, J.C.; Calvo-Mendez, C.; Flores-Carreon, A.; Lopez-Romero, E.
    Entamoeba histolytica: identification and properties of membrane-bound and soluble alpha-glucosidases (1999), Exp. Parasitol., 93, 109-115.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.2.1.106 Brij 35 at 0.12%: 98% activation Entamoeba histolytica
3.2.1.106 Triton X-100 77% activation Entamoeba histolytica

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.106 1-deoxynojirimycin 50% inhibition Entamoeba histolytica
3.2.1.106 castanospermine 15% inhibition Entamoeba histolytica
3.2.1.106 Mg2+ slight inhibition Entamoeba histolytica
3.2.1.106 Mn2+ slight inhibition Entamoeba histolytica
3.2.1.106 octyl-beta-glucoside
-
 Entamoeba histolytica
3.2.1.106 SDS strong inhibition Entamoeba histolytica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.106 0.036
-
 4-methylumbelliferyl-alpha-D-glucoside
-
 Entamoeba histolytica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.106 membrane membrane-bound Entamoeba histolytica 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.2.1.106 additional information metal ions not required Entamoeba histolytica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.106 Glc3Man9GlcNAc2 + H2O Entamoeba histolytica hydrolyses specifically terminal alpha1,2-linked glucose residue ?
-
 ?
3.2.1.106 Glc3Man9GlcNAc2 + H2O Entamoeba histolytica HM1:IMSS hydrolyses specifically terminal alpha1,2-linked glucose residue ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.106 Entamoeba histolytica
-
-
-
3.2.1.106 Entamoeba histolytica HM1:IMSS
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.106 trophozoite
-
 Entamoeba histolytica
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.106 4-methylumbelliferyl-alpha-D-glucoside + H2O
-
 Entamoeba histolytica 4-methylumbelliferone + D-glucose
-
 ?
3.2.1.106 4-methylumbelliferyl-alpha-D-glucoside + H2O
-
 Entamoeba histolytica HM1:IMSS 4-methylumbelliferone + D-glucose
-
 ?
3.2.1.106 Glc3Man9GlcNAc2 + H2O hydrolyses specifically terminal alpha1,2-linked glucose residue Entamoeba histolytica D-glucose + Glc2Man9GlcNAc2
-
 ?
3.2.1.106 Glc3Man9GlcNAc2 + H2O hydrolyses specifically terminal alpha1,2-linked glucose residue Entamoeba histolytica HM1:IMSS D-glucose + Glc2Man9GlcNAc2
-
 ?
3.2.1.106 Glc3Man9GlcNAc2 + H2O hydrolyses specifically terminal alpha1,2-linked glucose residue Entamoeba histolytica ?
-
 ?
3.2.1.106 Glc3Man9GlcNAc2 + H2O hydrolyses specifically terminal alpha1,2-linked glucose residue Entamoeba histolytica HM1:IMSS ?
-
 ?
3.2.1.106 additional information also acts, more slowly, on the corresponding glycolipids and glycopeptides Entamoeba histolytica ?
-
 ?
3.2.1.106 additional information p-nitrophenyl-alpha-D-glucopyranoside: not a substrate Entamoeba histolytica ?
-
 ?
3.2.1.106 additional information also acts, more slowly, on the corresponding glycolipids and glycopeptides Entamoeba histolytica HM1:IMSS ?
-
 ?
3.2.1.106 additional information p-nitrophenyl-alpha-D-glucopyranoside: not a substrate Entamoeba histolytica HM1:IMSS ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.106 47
-
-
 Entamoeba histolytica

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.106 6
-
-
 Entamoeba histolytica