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Literature summary extracted from
- Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum (1969), Biochem. J., 111, 91-95.
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.10.1.1 | 0.13 | - |
Glucosamine 2,6-disulfate | - |
Pedobacter heparinus |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.10.1.1 | cytoplasm | - |
Pedobacter heparinus | 5737 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.10.1.1 | Mg2+ | activation by 1 mM | Pedobacter heparinus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.10.1.1 | heparin + H2O | Pedobacter heparinus | degradation products of | ? + sulfate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.6.11 | Pedobacter heparinus | - |
- |
- |
| 3.10.1.1 | Pedobacter heparinus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.10.1.1 | - |
Pedobacter heparinus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.10.1.1 | glucosamine 2,6-disulfate + H2O | - |
Pedobacter heparinus | D-glucosamine 6-sulfate + sulfate | - |
ir | |
| 3.10.1.1 | heparin + H2O | degradation products of | Pedobacter heparinus | ? + sulfate | - |
? | |
| 3.10.1.1 | N-sulfo-D-glucosamine + H2O | - |
Pedobacter heparinus | D-glucosamine + sulfate | - |
ir | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 25 | - |
- |
Pedobacter heparinus |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 45 | - |
almost no activity | Pedobacter heparinus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 7 | - |
- |
Pedobacter heparinus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.10.1.1 | 6 | 8 | - |
Pedobacter heparinus |
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Release 2023.1 (January 2023)
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