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Literature summary extracted from

  • Fujiwara, H.; Takeshita, N.; Terano, Y.; Fitchen, J.H.; Tsujita, T.; Katagiri, Y.; Sato, F.; Yamada, Y.
    Expression of (S)-scoulerine 9-O-methyltransferase in Coptis japonica plants (1993), Phytochemistry, 34, 949-954.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.117 S-Adenosyl-L-methionine + (S)-scoulerine Coptis japonica the enzyme is responsible for a late step in the biosynthesis of berberine ?
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Organism

EC Number Organism UniProt Comment Textmining
2.1.1.117 Coptis japonica
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.117 cell culture activity of high berberine-producing cells is higher than that of non-selected cells Coptis japonica
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2.1.1.117 leaf low activity Coptis japonica
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2.1.1.117 root low activity Coptis japonica
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2.1.1.117 root high activity Coptis japonica
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2.1.1.117 root lateral Coptis japonica
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2.1.1.117 root main root Coptis japonica
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2.1.1.117 stem high activity Coptis japonica
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.117 S-Adenosyl-L-methionine + (S)-scoulerine
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Coptis japonica S-Adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine
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2.1.1.117 S-Adenosyl-L-methionine + (S)-scoulerine the enzyme is responsible for a late step in the biosynthesis of berberine Coptis japonica ?
-
?