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Literature summary extracted from

  • Boritzki, T.J.; Jackson, R.C.; Morris, H.P.; Weber, G.
    Guanosine-5'-phosphate synthetase and guanosine-5'-phosphate kinase in rat hepatomas and kidney tumors (1981), Biochim. Biophys. Acta, 658, 102-110.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.3.5.2 0.0044
-
 XMP
-
 Rattus norvegicus
6.3.5.2 0.0112
-
 GMP
-
 Rattus norvegicus
6.3.5.2 0.11
-
 MgATP2-
-
 Rattus norvegicus
6.3.5.2 0.21
-
 Gln
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.3.5.2 cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.5.2 Mg2+ required Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.5.2 83000
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.5.2 additional information Rattus norvegicus enzyme activity is linked with cellular proliferation in differentiating, regenerating and neoplastic tissues ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.5.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.5.2 bone marrow
-
 Rattus norvegicus
-
6.3.5.2 brain
-
 Rattus norvegicus
-
6.3.5.2 heart
-
 Rattus norvegicus
-
6.3.5.2 hepatoma cell line
-
 Rattus norvegicus
-
6.3.5.2 intestine mucosa Rattus norvegicus
-
6.3.5.2 kidney
-
 Rattus norvegicus
-
6.3.5.2 kidney tumor cell
-
 Rattus norvegicus
-
6.3.5.2 liver
-
 Rattus norvegicus
-
6.3.5.2 lung
-
 Rattus norvegicus
-
6.3.5.2 skeletal muscle
-
 Rattus norvegicus
-
6.3.5.2 spleen
-
 Rattus norvegicus
-
6.3.5.2 testis
-
 Rattus norvegicus
-
6.3.5.2 thymus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.5.2 ATP + XMP + Gln
-
 Rattus norvegicus AMP + diphosphate + GMP + Glu
-
 ?
6.3.5.2 additional information enzyme activity is linked with cellular proliferation in differentiating, regenerating and neoplastic tissues Rattus norvegicus ?
-
 ?
6.3.5.2 XMP + Mg-ATP2-
-
 Rattus norvegicus adenyl-XMP + diphosphate + Mg2+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3.5.2 7.6 7.8
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
6.3.5.2 7.6 7.8
-
 Rattus norvegicus