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Literature summary extracted from

  • Jurkowitz, M.S.; Horrocks, L.A.; Litsky, M.L.
    dentification and characterization of alkenyl hydrolase (lysoplasmalogenase) in microsomes and identification of a plasmalogen-active phospholipase A2 in cytosol of small intestinal epithelium (1999), Biochim. Biophys. Acta, 1437, 142-156.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.2 deoxycholate 3.2 mM, 50% inhibition Rattus norvegicus
3.3.2.2 iodoacetate 12 mM, 17% inhibition Rattus norvegicus
3.3.2.2 octyl glucoside 10 mM, 50% inhibition Rattus norvegicus
3.3.2.2 Phenylmethylsulfonylfluoride 6 mM 29% inhibition; 6 mM, 29% inhibition Rattus norvegicus
3.3.2.2 Triton X-100 0.09 mM, 50% inhibition Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.2 microsome 87% of the activity Rattus norvegicus
-
-
3.3.2.2 mitochondrion
-
 Rattus norvegicus 5739
-
3.3.2.2 mitochondrion 14% of the activity Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.3.2.2 1-(1-alkenyl)-sn-glycero-3-phosphocholine + H2O Rattus norvegicus
-
 aldehyde + sn-glycero-3-phosphocholine
-
 ?
3.3.2.2 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O Rattus norvegicus
-
 aldehyde + sn-glycero-3-phosphoethanolamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.2 small intestine epithelium Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.3.2.2 0.057
-
-
 Rattus norvegicus
3.3.2.2 0.07
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
3.3.2.2 -20°C, 50% glycerol, stable for more than 12 months Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.2 1-(1-alkenyl)-sn-glycero-3-phosphocholine + H2O
-
 Rattus norvegicus aldehyde + sn-glycero-3-phosphocholine
-
 ?
3.3.2.2 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O
-
 Rattus norvegicus aldehyde + sn-glycero-3-phosphoethanolamine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.3.2.2 6.8 7.4
-
 Rattus norvegicus
3.3.2.2 6.8 7.4 substrate 1-(1-alkenyl)-sn-glycero-3-phosphocholine Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.3.2.2 0.09
-
 Triton X-100
-
 Rattus norvegicus
3.3.2.2 10
-
 octyl glucoside
-
 Rattus norvegicus