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Literature summary extracted from

  • Sigrist, H.; Ronner, P.; Semenza, G.
    A hydrophobic form of the small-intestinal sucrase-isomaltase complex (1975), Biochim. Biophys. Acta, 406, 433-446.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.48 Tris concentration-dependent biphasic effect, first causing activation, fully competitive inhibition above pH 6.8, inhibition is stronger at alkaline pH values Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.48 8.4
-
 sucrose
-
 Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.2.1.48 Na+ low concentration: activation Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.48 140000
-
 SDS-PAGE, sucrase-isomaltase Oryctolagus cuniculus
3.2.1.48 220000
-
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.48 maltose + H2O Oryctolagus cuniculus
-
 2 glucose
-
 ?
3.2.1.48 sucrose + H2O Oryctolagus cuniculus
-
 D-glucose + D-fructose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.48 Oryctolagus cuniculus
-
 rabbit
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.2.1.48 0.1
-
-
 Oryctolagus cuniculus
3.2.1.48 17.5
-
-
 Oryctolagus cuniculus

Storage Stability

EC Number Storage Stability Organism
3.2.1.48 4°C or -20°C, 0.02% sodium azide, Triton X-100, several weeks, sucrase-isomaltase Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.48 maltose + H2O
-
 Oryctolagus cuniculus 2 glucose
-
 ?
3.2.1.48 sucrose + H2O
-
 Oryctolagus cuniculus D-glucose + D-fructose
-
 ?