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Literature summary extracted from

  • Lee, B.H.; Hartman, S.C.
    Preferential utilization of glutamine for amination of xanthosine 5'-phosphate to guanosine 5'-phosphate by purified enzymes from Escherichia coli (1974), Biochem. Biophys. Res. Commun., 60, 918-925.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.5.2 6-diazo-5-oxo-L-norleucine irreversible inhibition is dependent on presence of XMP, ATP and Mg2+ Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.5.2 60000
-
2 * 60000, SDS-PAGE in presence of 2-mercaptoethanol Escherichia coli
6.3.5.2 125000
-
gel filtration Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.3.5.2 Escherichia coli
-
-
-
6.3.5.2 Escherichia coli
-
B
-
6.3.5.2 Escherichia coli B / ATCC 11303
-
B
-
6.3.5.2 Escherichia coli B96
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.5.2 a single enzyme is responsible for Gln-dependent and NH4+-dependent reaction Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.5.2 ATP + XMP + Gln a single enzyme is responsible for Gln-dependent and NH4+ dependent reaction Escherichia coli AMP + diphosphate + GMP + Glu
-
?
6.3.5.2 ATP + XMP + Gln a single enzyme is responsible for Gln-dependent and NH4+ dependent reaction Escherichia coli B / ATCC 11303 AMP + diphosphate + GMP + Glu
-
?
6.3.5.2 ATP + XMP + Gln a single enzyme is responsible for Gln-dependent and NH4+ dependent reaction Escherichia coli B96 AMP + diphosphate + GMP + Glu
-
?
6.3.5.2 ATP + XMP + NH4+ a single enzyme is responsible for Gln-dependent and NH4+ dependent reaction Escherichia coli AMP + diphosphate + GMP
-
?
6.3.5.2 ATP + XMP + NH4+ a single enzyme is responsible for Gln-dependent and NH4+ dependent reaction Escherichia coli B / ATCC 11303 AMP + diphosphate + GMP
-
?
6.3.5.2 ATP + XMP + NH4+ a single enzyme is responsible for Gln-dependent and NH4+ dependent reaction Escherichia coli B96 AMP + diphosphate + GMP
-
?

Subunits

EC Number Subunits Comment Organism
6.3.5.2 dimer 2 * 60000, SDS-PAGE in presence of 2-mercaptoethanol Escherichia coli