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Literature summary extracted from

  • Quirk, S.; Bessman, M.J.
    dGTP triphosphohydrolase, a unique enzyme confined to members of the family Enterobacteriaceae (1991), J. Bacteriol., 173, 6665-6669.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.5.1 230000
-
 gel filtration Escherichia coli
3.1.5.1 230000
-
 enzyme is present only in enteric bacteria Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.5.1 dGTP + H2O Salmonella enterica subsp. enterica serovar Typhimurium
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Escherichia coli
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Klebsiella aerogenes
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Serratia marcescens
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Proteus mirabilis
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Citrobacter freundii
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Hafnia alvei
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Yersinia enterocolitica
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Klebsiella oxytoca
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Cedecea davisae
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Salmonella enterica subsp. enterica serovar Gallinarum
-
 deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O Shigella boydii
-
 deoxyguanosine + triphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.5.1 Cedecea davisae
-
-
-
3.1.5.1 Citrobacter freundii
-
-
-
3.1.5.1 Escherichia coli
-
-
-
3.1.5.1 Hafnia alvei
-
-
-
3.1.5.1 Klebsiella aerogenes
-
-
-
3.1.5.1 Klebsiella oxytoca
-
-
-
3.1.5.1 Proteus mirabilis
-
-
-
3.1.5.1 Salmonella enterica subsp. enterica serovar Gallinarum
-
-
-
3.1.5.1 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
3.1.5.1 Serratia marcescens
-
-
-
3.1.5.1 Shigella boydii
-
-
-
3.1.5.1 Yersinia enterocolitica
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.5.1
-
 Escherichia coli
3.1.5.1 partial Salmonella enterica subsp. enterica serovar Typhimurium
3.1.5.1 partial Klebsiella aerogenes
3.1.5.1 partial Proteus mirabilis
3.1.5.1 partial Citrobacter freundii
3.1.5.1 partial Hafnia alvei
3.1.5.1 partial Yersinia enterocolitica
3.1.5.1 partial Klebsiella oxytoca
3.1.5.1 partial Cedecea davisae
3.1.5.1 partial Salmonella enterica subsp. enterica serovar Gallinarum
3.1.5.1 partial, no precipitation with nucleic acids Serratia marcescens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.5.1 dGTP + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Escherichia coli deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Klebsiella aerogenes deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Serratia marcescens deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Proteus mirabilis deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Citrobacter freundii deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Hafnia alvei deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Yersinia enterocolitica deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Klebsiella oxytoca deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Cedecea davisae deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Salmonella enterica subsp. enterica serovar Gallinarum deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O
-
 Shigella boydii deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Salmonella enterica subsp. enterica serovar Typhimurium deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Escherichia coli deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Klebsiella aerogenes deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Serratia marcescens deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Proteus mirabilis deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Citrobacter freundii deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Hafnia alvei deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Yersinia enterocolitica deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Klebsiella oxytoca deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Cedecea davisae deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Salmonella enterica subsp. enterica serovar Gallinarum deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O highly specific for Shigella boydii deoxyguanosine + triphosphate
-
 ?
3.1.5.1 dGTP + H2O no activity on dGDP Escherichia coli deoxyguanosine + triphosphate
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.5.1 55 60
-
 Salmonella enterica subsp. enterica serovar Typhimurium
3.1.5.1 55 60
-
 Klebsiella aerogenes
3.1.5.1 55 60
-
 Serratia marcescens
3.1.5.1 55 60
-
 Proteus mirabilis
3.1.5.1 55 60
-
 Citrobacter freundii
3.1.5.1 55 60
-
 Hafnia alvei
3.1.5.1 55 60
-
 Yersinia enterocolitica
3.1.5.1 55 60
-
 Klebsiella oxytoca
3.1.5.1 55 60
-
 Cedecea davisae
3.1.5.1 55 60
-
 Salmonella enterica subsp. enterica serovar Gallinarum
3.1.5.1 55 60
-
 Shigella boydii
3.1.5.1 55 60 full activity after 1 h Escherichia coli