BRENDA - Enzyme Database

Sphingomyelinase D: A pathogenic agent produced by bacteria and arthropods

Truett III, A.P.; King, L.E.; Adv. Lipid Res. 26, 275-291 (1993)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
3.1.4.41
expression in Escherichia coli
Photobacterium damselae
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.41
additional information
inhibition of erythrocyte lysis by staphylococcal beta-haemolysin
Corynebacterium pseudotuberculosis
3.1.4.41
additional information
-
Loxosceles reclusa
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.4.41
Ca2+
required for activity
Corynebacterium pseudotuberculosis
3.1.4.41
Mg2+
required for activity
Corynebacterium pseudotuberculosis
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.4.41
16000
-
gel filtration
Corynebacterium pseudotuberculosis
3.1.4.41
31000
-
SDS-PAGE
Corynebacterium pseudotuberculosis
3.1.4.41
52000
-
gel filtration
Photobacterium damselae
3.1.4.41
69000
-
SDS-PAGE
Photobacterium damselae
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.4.41
Corynebacterium pseudotuberculosis
-
-
-
3.1.4.41
Corynebacterium ulcerans
-
-
-
3.1.4.41
Loxosceles reclusa
-
-
-
3.1.4.41
Photobacterium damselae
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.41
lysophosphatidylcholine + H2O
-
135485
Corynebacterium pseudotuberculosis
lysophosphatidic acid + choline
-
-
-
?
3.1.4.41
lysophosphatidylcholine + H2O
-
135485
Loxosceles reclusa
lysophosphatidic acid + choline
-
-
-
?
3.1.4.41
phosphatidylcholine
-
135485
Photobacterium damselae
?
-
-
-
?
3.1.4.41
phosphatidylethanolamine + H2O
-
135485
Photobacterium damselae
?
-
-
-
?
3.1.4.41
sphingomyelin + H2O
-
135485
Corynebacterium ulcerans
N-acylsphingosylphosphate + choline
-
135485
Corynebacterium ulcerans
?
3.1.4.41
sphingomyelin + H2O
-
135485
Corynebacterium pseudotuberculosis
N-acylsphingosylphosphate + choline
-
135485
Corynebacterium pseudotuberculosis
?
3.1.4.41
sphingomyelin + H2O
-
135485
Loxosceles reclusa
N-acylsphingosylphosphate + choline
-
135485
Loxosceles reclusa
?
3.1.4.41
sphingomyelin + H2O
-
135485
Photobacterium damselae
N-acylsphingosylphosphate + choline
-
135485
Photobacterium damselae
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.1.4.41
expression in Escherichia coli
Photobacterium damselae
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.41
additional information
inhibition of erythrocyte lysis by staphylococcal beta-haemolysin
Corynebacterium pseudotuberculosis
3.1.4.41
additional information
-
Loxosceles reclusa
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.4.41
Ca2+
required for activity
Corynebacterium pseudotuberculosis
3.1.4.41
Mg2+
required for activity
Corynebacterium pseudotuberculosis
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.4.41
16000
-
gel filtration
Corynebacterium pseudotuberculosis
3.1.4.41
31000
-
SDS-PAGE
Corynebacterium pseudotuberculosis
3.1.4.41
52000
-
gel filtration
Photobacterium damselae
3.1.4.41
69000
-
SDS-PAGE
Photobacterium damselae
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.41
lysophosphatidylcholine + H2O
-
135485
Corynebacterium pseudotuberculosis
lysophosphatidic acid + choline
-
-
-
?
3.1.4.41
lysophosphatidylcholine + H2O
-
135485
Loxosceles reclusa
lysophosphatidic acid + choline
-
-
-
?
3.1.4.41
phosphatidylcholine
-
135485
Photobacterium damselae
?
-
-
-
?
3.1.4.41
phosphatidylethanolamine + H2O
-
135485
Photobacterium damselae
?
-
-
-
?
3.1.4.41
sphingomyelin + H2O
-
135485
Corynebacterium ulcerans
N-acylsphingosylphosphate + choline
-
135485
Corynebacterium ulcerans
?
3.1.4.41
sphingomyelin + H2O
-
135485
Corynebacterium pseudotuberculosis
N-acylsphingosylphosphate + choline
-
135485
Corynebacterium pseudotuberculosis
?
3.1.4.41
sphingomyelin + H2O
-
135485
Loxosceles reclusa
N-acylsphingosylphosphate + choline
-
135485
Loxosceles reclusa
?
3.1.4.41
sphingomyelin + H2O
-
135485
Photobacterium damselae
N-acylsphingosylphosphate + choline
-
135485
Photobacterium damselae
?