Any feedback?
Literature summary extracted from
- Cytidine 5'-phosphate-N-acetylneuraminic acid hydrolase in calf kidney: properties and subcellular distribution (1974), Biochem. Soc. Trans., 2, 642-645.
No PubMed abstract available
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.40 | Triton X-100 | increase of enzyme activity | Bos taurus |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.40 | 2-mercaptoethanol | 60% inhibition at 5 mM | Bos taurus | |
| 3.1.4.40 | EDTA | - |
Bos taurus | |
| 3.1.4.40 | Mn2+ | slight inhibition at lower concentrations | Bos taurus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.4.40 | 0.6 | - |
CMP-N-acylneuraminate | - |
Bos taurus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.4.40 | microsome | - |
Bos taurus | - |
- |
| 3.1.4.40 | mitochondrion | - |
Bos taurus | 5739 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.4.40 | Ca2+ | - |
Bos taurus | |
| 3.1.4.40 | Mg2+ | - |
Bos taurus | |
| 3.1.4.40 | Mn2+ | increased activity at higher concentrations | Bos taurus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | Bos taurus | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.4.40 | Bos taurus | - |
calf | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.4.40 | kidney | cortex | Bos taurus | - |
| 3.1.4.40 | liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.40 | additional information | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | - |
Bos taurus | CMP + N-acylneuraminate | - |
? | |
| 3.1.4.40 | CMP-N-acylneuraminate + H2O | - |
Bos taurus | ? | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.40 | 45 | - |
- |
Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.4.40 | 8.8 | 9 | - |
Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
