BRENDA - Enzyme Database

Properties of phospholipase C isolated from rat liver lysosomes

Matsuzawa, Y.; Hostetler, K.Y.; J. Biol. Chem. 255, 646-652 (1980)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.3
Ca2+
-
Rattus norvegicus
3.1.4.3
Co2+
-
Rattus norvegicus
3.1.4.3
Mg2+
-
Rattus norvegicus
3.1.4.3
Mn2+
-
Rattus norvegicus
3.1.4.3
sodium deoxycholate
-
Rattus norvegicus
3.1.4.3
Zn2+
-
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.4.3
lysosome
-
Rattus norvegicus
5764
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.4.3
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.3
liver
-
Rattus norvegicus
-
Storage Stability
EC Number
Storage Stability
Organism
3.1.4.3
-60°C, for one year, activity only slightly decreased
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.3
1,2-dioleoylphosphatidylcholine + H2O
-
135301
Rattus norvegicus
1,2-dioleoylglycerol + phosphorylcholine
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylcholine + H2O
-
135301
Rattus norvegicus
1,2-diacylglycerol + phosphorylcholine
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylethanolamine + H2O
-
135301
Rattus norvegicus
phosphorylethanolamine + diacylglycerol
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylglycerol + H2O
-
135301
Rattus norvegicus
1,2-diacylglycerol + phosphate
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylinositol + H2O
-
135301
Rattus norvegicus
inositol monophosphate + diacylglycerol
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylserine + H2O
-
135301
Rattus norvegicus
phosphorylserine + diacylglycerol
-
135301
Rattus norvegicus
?
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.1.4.3
4.4
-
substrate: 1,2-dioleoyl-3-phosphatidylcholine
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.3
Ca2+
-
Rattus norvegicus
3.1.4.3
Co2+
-
Rattus norvegicus
3.1.4.3
Mg2+
-
Rattus norvegicus
3.1.4.3
Mn2+
-
Rattus norvegicus
3.1.4.3
sodium deoxycholate
-
Rattus norvegicus
3.1.4.3
Zn2+
-
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.4.3
lysosome
-
Rattus norvegicus
5764
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.3
liver
-
Rattus norvegicus
-
Storage Stability (protein specific)
EC Number
Storage Stability
Organism
3.1.4.3
-60°C, for one year, activity only slightly decreased
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.3
1,2-dioleoylphosphatidylcholine + H2O
-
135301
Rattus norvegicus
1,2-dioleoylglycerol + phosphorylcholine
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylcholine + H2O
-
135301
Rattus norvegicus
1,2-diacylglycerol + phosphorylcholine
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylethanolamine + H2O
-
135301
Rattus norvegicus
phosphorylethanolamine + diacylglycerol
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylglycerol + H2O
-
135301
Rattus norvegicus
1,2-diacylglycerol + phosphate
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylinositol + H2O
-
135301
Rattus norvegicus
inositol monophosphate + diacylglycerol
-
135301
Rattus norvegicus
?
3.1.4.3
phosphatidylserine + H2O
-
135301
Rattus norvegicus
phosphorylserine + diacylglycerol
-
135301
Rattus norvegicus
?
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.1.4.3
4.4
-
substrate: 1,2-dioleoyl-3-phosphatidylcholine
Rattus norvegicus